Results 241 to 248 of about 46,994 (248)
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Identification of GATA3 binding sites in Jurkat cells
Gene, 2009Determining binding sites of transcription factors is important for understanding the transcriptional control of target genes. Although a transcription factor GATA3 plays a pivotal role in Th2 lymphocyte development, its physiological role is not clearly defined because the target genes remain largely unknown.
Masahiro, Okazaki +4 more
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GATA3 Positivity in Benign Radiated Prostate Glands
American Journal of Surgical Pathology, 2017Histologic changes following radiation therapy to the prostate include multilayering of glands, atrophy, squamous metaplasia, and often marked random nuclear atypia. We have seen multiple consultation cases where the differential diagnosis of these radiated prostate glands included urothelial carcinoma, with multilayered to solid-appearing ...
Sara E, Wobker +2 more
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The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation
Journal of Cellular Physiology, 2017GATA3 is a key transcription factor in cell fate determination and its dysregulation has been implicated in various types of malignancies. However, how the abundance and function of GATA3 are regulated remains unclear. Here, we report that GATA3 is physically associated with FBXW7α, and FBXW7α destabilizes GATA3 through assembly of a SKP1‐CUL1‐F‐box E3
Nan, Song +8 more
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Value of GATA3 Immunostaining in Tumor Diagnosis
Advances in Anatomic Pathology, 2013GATA3 is a member of a group of zinc-finger transcription factors that is involved in cell development and differentiation. Recent studies have shown that, among tumors, GATA3 is commonly expressed in both urothelial tumors and breast epithelial neoplasms. With the exception of salivary gland and parathyroid tumors, GATA3 has been reported to be either
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[HDR syndrome (GATA3 haploinsufficiency syndrome)].
Nihon rinsho. Japanese journal of clinical medicine, 2006Takahiro, Mochizuki +3 more
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Immunoexpression of GATA3 in Renal Neoplasms
Journal of the American Society of CytopathologyXiaoqi Lin, Ximing Yang
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