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Identification of GATA3 binding sites in Jurkat cells

Gene, 2009
Determining binding sites of transcription factors is important for understanding the transcriptional control of target genes. Although a transcription factor GATA3 plays a pivotal role in Th2 lymphocyte development, its physiological role is not clearly defined because the target genes remain largely unknown.
Masahiro, Okazaki   +4 more
openaire   +2 more sources

GATA3 Positivity in Benign Radiated Prostate Glands

American Journal of Surgical Pathology, 2017
Histologic changes following radiation therapy to the prostate include multilayering of glands, atrophy, squamous metaplasia, and often marked random nuclear atypia. We have seen multiple consultation cases where the differential diagnosis of these radiated prostate glands included urothelial carcinoma, with multilayered to solid-appearing ...
Sara E, Wobker   +2 more
openaire   +2 more sources

The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation

Journal of Cellular Physiology, 2017
GATA3 is a key transcription factor in cell fate determination and its dysregulation has been implicated in various types of malignancies. However, how the abundance and function of GATA3 are regulated remains unclear. Here, we report that GATA3 is physically associated with FBXW7α, and FBXW7α destabilizes GATA3 through assembly of a SKP1‐CUL1‐F‐box E3
Nan, Song   +8 more
openaire   +2 more sources

Value of GATA3 Immunostaining in Tumor Diagnosis

Advances in Anatomic Pathology, 2013
GATA3 is a member of a group of zinc-finger transcription factors that is involved in cell development and differentiation. Recent studies have shown that, among tumors, GATA3 is commonly expressed in both urothelial tumors and breast epithelial neoplasms. With the exception of salivary gland and parathyroid tumors, GATA3 has been reported to be either
openaire   +2 more sources

[HDR syndrome (GATA3 haploinsufficiency syndrome)].

Nihon rinsho. Japanese journal of clinical medicine, 2006
Takahiro, Mochizuki   +3 more
openaire   +1 more source

Immunoexpression of GATA3 in Renal Neoplasms

Journal of the American Society of Cytopathology
Xiaoqi Lin, Ximing Yang
openaire   +1 more source

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