Results 101 to 110 of about 283,536 (308)
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
FEBS Open Bio, EarlyView.In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785
eLifeVoltage-gated K+ channels play central roles in human physiology, in health, and disease. A repertoire of inhibitors that are both potent and specific would, therefore, be of great value.
Shan Zhang +4 more
doaj +1 more source
Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen +6 more
wiley +1 more source
Dynamic liquid film nanochannels for adjustable ion and molecule transport
Nano ResearchGating, a fundamental feature of biological nanochannels, enables the intelligent regulation of ion and molecule transport in response to specific requirements.
Chunxiao Liang +5 more
doaj +1 more source
“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez +29 more
wiley +1 more source
Trypanosomes at the Gates [PDF]
Science, 2005 L ike many colleagues, I sometimes thought I'd never see the day when three small parasites would be so celebrated. After all, why should people outside of the small cohort of dedicated scientists and sponsors pay any attention to these “Tritryps”— Trypanosoma brucei, Trypanosoma cruzi , and Leishmania major —whose genomes appear in this issue of ...
openaire +2 more sources
Auditory Sensory Gating: Effects of Noise
BiologyCortical auditory evoked potentials (CAEPs) indicate that noise degrades auditory neural encoding, causing decreased peak amplitude and increased peak latency.
Fan-Yin Cheng, Julia Campbell, Chang Liu
doaj +1 more source
, 2010 Deficit of sensory gating in schizophrenia patients was explored in gating-out and gating-in paradigms. A pair of identical clicks was presented in gating-out paradigm.
N. Boutros, A. Vedeniapin, K. Gjini
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source