Results 211 to 220 of about 37,179 (261)

SDrecall: a sensitive approach for variant detection in segmental duplications. [PDF]

Genome Biol
Yang XT, She CH, Zhang C, Leung D, Yang J, Chan KW, Duque JSR, Lau YL, Yang W.   +8 more
europepmc   +1 more source

Genetic Evolution in BRCA1‐Associated Breast Cancer Reveals Early Driver Mutations Shaping Tumor Features and Prognosis

Cancer Science, Volume 117, Issue 10, Page 2863-2876, October 2026.
Multi‐region sequencing of 57 BRCA1‐associated breast cancers identified TP53 as the dominant initial driver, defining a triple‐negative subgroup with biallelic BRCA1 loss and elevated genomic instability. TP53 truncating mutations were enriched in BRCA1 carriers and linked to reduced HRD, EMT activation, and a trend toward worse survival.
Li Hu, Zhongwu Li, Qiting Wan, Xingyu Liao, Yaxin Zhang, Qian Liu, Xinyun Ding, Hua Meng, Yifan Wu, Jie Sun, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie   +13 more
wiley   +1 more source

A comparative analysis dataset for improving genuine SNP identification in ancient maize aDNA. [PDF]

Data Brief
Chen H, Madzima TF.
europepmc   +1 more source

Elucidating the Role of SET as a Key Contributor to Neurodevelopmental Disability Within the 9q34.11 Deletion Syndrome Interval

Clinical Genetics, Volume 110, Issue 4, Page 438-448, October 2026.
This study reports a female proband with a de novo 9q34.11 deletion affecting SET, who underwent a 28‐year diagnostic odyssey after an atypical Rett syndrome clinical diagnosis. Genomic and proteomics analyses confirmed SET haploinsufficiency, refining the critical 9q34.11 region, and supporting speech therapy benefits in improving meaningful ...
Angelo Condell, Elaine Zhang, Tim Sikora, Sean Massey, Nicole J. Van Bergen, Min Wang, Cas Simons, Katrina M. Bell, Daniella H. Hock, David A. Stroud, David Francis, Wendy A. Gold, Martin B. Delatycki, John Christodoulou, Simranpreet Kaur   +14 more
wiley   +1 more source

High‑resolution recombination landscape in Iranian native chicken ecotypes: Elevated hotspot density and candidate genes for heat and drought adaptation. [PDF]

Poult Sci
Saadatabadi LM, Kharrati-Koopaee H, Ghanatsaman ZA, Wang MS, Esmailizadeh A.   +4 more
europepmc   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, Volume 59, Issue 10, Page 2143-2163, October 2026.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Genome Skimming Reveals Genetic Diversity in 220 Papaver Individuals from China. [PDF]

Sci Data
Chen F, Gong Y, Zhang Z, Chang Y, Su Y, Wang X, Zhang M, Yang Z, Wei Y.   +8 more
europepmc   +1 more source

Genomic Vulnerability of a Threatened Possum in a Biodiversity and Climate Change Hotspot

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Spatial variation in the magnitude and pace of climate change impacts means some species will be more affected than others. This includes those occurring within global biodiversity hotspots, regions with exceptional concentrations of endemic species that have often been shaped by long‐term climatic stability.
Grace I. Marsh, Sean James Buckley, Daniel J. White, Adrian F. Wayne, Bryony J. Palmer, Nicola J. Mitchell   +5 more
wiley   +1 more source

TriosCompass: a snakemake workflow for integrated detection of SNVs, indels, STRs, and structural de novo variants in parent-child trios. [PDF]

Bioinformatics
Zhu W, Yeager M, Dawson ET, Jain K, Hicks B, Dean M, Chanock SJ, Wong WSW.   +7 more
europepmc   +1 more source

Blocks of Identity by Descent Reveal the Dual Role Played by Reef Fish Larvae for Retention and Dispersal

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Isolation by distance, whereby genetic distance between individuals or populations increases with geographic distance, is a fundamental population genetic pattern that is observed across a broad range of taxa and spatial scales. This pattern can be driven by dispersal limitation and be thereby informative about dispersal rate (σ$$ \sigma ...
Nina Tombers, Francisco Campuzano‐Jiménez, Martin Helmkampf, Janina Fuß, W. Owen McMillan, Oscar Puebla   +5 more
wiley   +1 more source