Results 101 to 110 of about 798,500 (344)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Gauge engineering and propagators

open access: yesEPJ Web of Conferences, 2017
Beyond perturbation theory gauge-fixing becomes more involved due to the Gribov-Singer ambiguity: The appearance of additional gauge copies requires to define a procedure how to handle them.
Maas Axel
doaj   +1 more source

Finite N Matrix Models of Noncommutative Gauge Theory

open access: yes, 1999
We describe a unitary matrix model which is constructed from discrete analogs of the usual projective modules over the noncommutative torus and use it to construct a lattice version of noncommutative gauge theory.
Ambjorn, J.   +3 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

CANONICAL STRUCTURE OF GAUGE INVARIANCE PROCA'S ELECTRODYNAMICS THEORY

open access: yesMomento, 2018
Proca's electrodynamics describes a theory of massive photons which is not gauge invariant. In this paper we show that the gauge invariance is recovered if a scalar field is properly incorporated into the theory.
German E. Zambrano, Bruto M. Pimentel
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Minimal gauge invariant and gauge fixed actions for massive higher-spin fields

open access: yesJournal of High Energy Physics, 2019
Inspired by the rich structure of covariant string field theory, we propose a minimal gauge invariant action for general massive integer spin n field. The action consists of four totally symmetric tensor fields of order respectively n, n − 1, n − 2 and n
Masako Asano
doaj   +1 more source

Tuning the Topological $θ$-Angle in Cold-Atom Quantum Simulators of Gauge Theories [PDF]

open access: green, 2022
Jad C. Halimeh   +3 more
openalex   +1 more source

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