Results 121 to 130 of about 7,058,876 (385)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Finite N Matrix Models of Noncommutative Gauge Theory
, 1999 We describe a unitary matrix model which is constructed from discrete analogs of the usual projective modules over the noncommutative torus and use it to construct a lattice version of noncommutative gauge theory.
Ambjorn, J. +3 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Gauge invariance in a Z_2 hamiltonian lattice gauge theory
, 2005 We propose an efficient variational method for $Z_2$ lattice gauge theory based on the matrix product ansatz. The method is applied to ladder and square lattices.
Sugihara, Takanori
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Journal of High Energy Physics, 2018 We study excitations of LLM geometries. These geometries arise from the backreaction of a condensate of giant gravitons. Excitations of the condensed branes are open strings, which give rise to an emergent Yang-Mills theory at low energy.
Robert de Mello Koch +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Physics Letters BIn this study, we demonstrate that an inviscid fluid in a near-equilibrium state, when viewed in the Lagrangian picture in d+1 spacetime dimensions, can be reformulated as a (d−1)-form gauge theory.
V. Taghiloo, M.H. Vahidinia
doaj +1 more source