Results 31 to 40 of about 11,061,498 (228)
Science and Technology for Energy TransitionSurrogate models have become a widely used solution for reducing computation times along design processes. In this work, a Gaussian Process surrogate model is built and used to predict the performance and losses of a wound field electrical machine in a ...
Mazloum Rebecca +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
SCADA based nonparametric models for condition monitoring of a wind turbine
The Journal of Engineering, 2019 High operation and maintenance costs for offshore wind turbines push up the LCOE of offshore wind energy. Unscheduled maintenance due to unanticipated failures is the most prominent driver of the maintenance cost which reinforces the drive towards ...
Ravi Kumar Pandit +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Geomatics, Natural Hazards & Risk, 2020 Deformation of surrounding rock is widely monitored to discover surrounding rock behaviors for purpose of event forecasting. This article aims to present a comparative study on surrounding rock nonlinear deformation prediction using computational ...
Peng He, Fei Xu, Shang-qu Sun
doaj +1 more source
Harmonic State Estimation Method Based on Bayesian Optimized Elastic Network Regression
Zhongguo dianli, 2022 When the regression algorithm is used to estimate the harmonic state of power system, the high correlation between harmonic sources will cause the ill condition of the normal matrix, which will significantly affect the accuracy of harmonic estimation. In
Siqi MA, Zhong WANG
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Gaussian Process Graph-Based Discriminant Analysis for Hyperspectral Images Classification
Remote Sensing, 2019 Dimensionality Reduction (DR) models are highly useful for tackling Hyperspectral Images (HSIs) classification tasks. They mainly address two issues: the curse of dimensionality with respect to spectral features, and the limited number of labeled ...
Xin Song +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source