Results 41 to 50 of about 291,981 (317)

Elliptic equations and Gaussian processes [PDF]

open access: yesJournal of Functional Analysis, 1980
AbstractWe consider a Gaussian process P on s(Rd) generated by a polynomial in the Laplace operator. We prove some support properties for P. As a byproduct we strenghten earlier results on the stochastic Dirichlet problem on bounded regions Λ ⊂ Rd. We describe in this way the conditional P-distribution of the restriction to Λ of s(Rd), supposing ϑ is ...
G. Benfatto   +2 more
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Gaussian Process Graph-Based Discriminant Analysis for Hyperspectral Images Classification

open access: yesRemote Sensing, 2019
Dimensionality Reduction (DR) models are highly useful for tackling Hyperspectral Images (HSIs) classification tasks. They mainly address two issues: the curse of dimensionality with respect to spectral features, and the limited number of labeled ...
Xin Song   +3 more
doaj   +1 more source

Distributed Gaussian Processes

open access: yes, 2015
Copyright © 2015 by the author(s).To scale Gaussian processes (GPs) to large data sets we introduce the robust Bayesian Committee Machine (rBCM), a practical and scalable product-of-experts model for large-scale distributed GP regression. Unlike state-of-the-art sparse GP approximations, the rBCM is conceptually simple and does not rely on inducing or ...
Deisenroth, MP, Ng, JW
openaire   +5 more sources

Skew Gaussian processes for classification [PDF]

open access: yesMachine Learning, 2020
AbstractGaussian processes (GPs) are distributions over functions, which provide a Bayesian nonparametric approach to regression and classification. In spite of their success, GPs have limited use in some applications, for example, in some cases a symmetric distribution with respect to its mean is an unreasonable model. This implies, for instance, that
Alessio Benavoli   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Efficient learning variable impedance control for industrial robots [PDF]

open access: yesBulletin of the Polish Academy of Sciences: Technical Sciences, 2019
Compared with the robots, humans can learn to perform various contact tasks in unstructured environments by modulating arm impedance characteristics. In this article, we consider endowing this compliant ability to the industrial robots to effectively ...
C. Li, Z. Zhang, G. Xia, X. Xie, Q. Zhu
doaj   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

open access: yesFEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

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