Results 41 to 50 of about 28,529 (123)

13C NMR Relaxation Analysis of Protein GB3 for the Assessment of Sidechain Dynamics Predictions by Current AMBER and CHARMM Force Fields.

Journal of Chemical Theory and Computation, 2020
Molecular simulations with seven current AMBER- and CHARMM-based force fields yield markedly differing internal bond vector autocorrelation function predictions for many of the 223 methine and methylene H-C bonds of the 56-residue protein GB3.
Janet S. Anderson, G. Hernández, D. LeMaster   +2 more
semanticscholar   +1 more source

Monitoring mangrove-based blue carbon ecosystems using UAVs: a review

Geocarto International
Blue carbon habitats, including mangrove forests, salt marshes, and seagrass beds, play a crucial role in sequestering organic carbon, mitigating global warming, and protecting coastlines and local livelihoods.
Nurul Asyiqin Abu Bakar, Wan Shafrina Wan Mohd Jaafar, Khairul Nizam Abdul Maulud, Aisyah Marliza Muhmad Kamarulzaman, Siti Nor Maizah Saad, Midhun Mohan   +5 more
doaj   +1 more source

Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling.

Cellular Physiology and Biochemistry, 2019
BACKGROUND/AIMS Fabry disease (FD) is a lysosomal storage disorder characterized by impaired alpha-galactosidase A (α-Gal A) enzyme activity due to mutations in the GLA gene. While virtually all tissues are affected, renal damage is particularly critical
Fabian Braun, Linda Blomberg, S. Brodesser, M. Liebau, B. Schermer, T. Benzing, C. Kurschat   +6 more
semanticscholar   +1 more source

A large-scale extraction framework for mapping urban in-formal settlements using remote sensing and semantic segmentation

Geocarto International
Urban informal settlements (UISs) are densely populated and poorly developed residential areas in urban areas. The mapping of UISs using remote sensing is crucial for urban planning and management.
Yanan Zhang, Chen Lu, Jiao Wang, Fuguang Du   +3 more
doaj   +1 more source

Drought susceptibility modeling with geospatial techniques and AHP model: a case of Bilate River Watershed, Central Rift Valley of Ethiopia

Geocarto International
Drought continues to be the worst natural hazard in the world affecting ecosystems, economies and overall human welfare with severe consequences in developing countries.
Ashenafi Burka, Birhanu Biazin, Woldeamlak Bewket   +2 more
doaj   +1 more source

Effectiveness of plasma lyso-Gb3 as a biomarker for selecting high-risk patients with Fabry disease from multispecialty clinics for genetic analysis

Genetics in Medicine, 2018
Plasma globotriaosylsphingosine (lyso-Gb3) is a promising secondary screening biomarker for Fabry disease. Here, we examined its applicability as a primary screening biomarker for classic and late-onset Fabry disease in males and females.
H. Maruyama, Kaori Miyata, Mariko Mikame, Atsumi Taguchi, Gui-Li Chu, Masaru Shimura, K. Murayama, Takeshi Inoue, S. Yamamoto, K. Sugimura, Koichi Tamita, T. Kawasaki, J. Kajihara, Akifumi Onishi, H. Sugiyama, Teiko Sakai, I. Murata, Takamasa Oda, Shigeru Toyoda, K. Hanawa, Takeo Fujimura, S. Ura, Mimiko Matsumura, H. Takano, Satoshi Yamashita, Gaku Matsukura, R. Tazawa, T. Shiga, M. Ebato, H. Satoh, S. Ishii   +30 more
semanticscholar   +1 more source

Enhancing spatial resolution of drought monitoring through a novel random forest-based GRACE drought index: a case study in Central Yunnan

Geocarto International
The original coarse spatial resolution of Gravity Recovery and Climate Experiment (GRACE) data limits its application in small and medium-scale areas.
Xia Wang, Wei Zheng, Wenjie Yin, Keke Xu, Hebing Zhang, Weiwei Lei   +5 more
doaj   +1 more source

Plasma lyso-Gb3: a biomarker for monitoring fabry patients during enzyme replacement therapy

Clinical and Experimental Nephrology, 2018
BackgroundRecently, globotriaosylsphingosine (lyso-Gb3) has attracted interest as a biomarker of Fabry disease. However, little is known regarding its utility for the evaluation of the therapeutic efficacy.MethodWe measured plasma lyso-Gb3 concentration ...
H. Sakuraba, Tadayasu Togawa, T. Tsukimura, Hiroshi Kato   +3 more
semanticscholar   +1 more source

Hyperspectral identification of travertine state in Huanglong by the PSO-BPNN method

Geocarto International
The Huanglong Scenic and Historic Interest Area in China, a UNESCO World Heritage Site, is famous for its large-scale, diverse, intricately structured, and brightly colored surface travertine landscapes.
Menghui Xu, Weihong Wang, Jialun Cai, Qunwei Dai, Jing Fan, Sicheng Li   +5 more
doaj   +1 more source

Lyso-Gb3 modulates the gut microbiota and decreases butyrate production

Scientific Reports, 2019
Fabry disease is a rare X-linked lysosomal storage disorder resulting from deficient activity of α-galactosidase A, leading to the accumulation of glycosphingolipids such as globotriaosylsphingosine (lyso-Gb3).
J. Aguilera-Correa, Patricia Madrazo-Clemente, María del Carmen Martínez-Cuesta, C. Peláez, A. Ortiz, María Dolores Sánchez-Niño, J. Esteban, T. Requena   +7 more
semanticscholar   +1 more source