Results 1 to 10 of about 19,114 (240)
Анналы клинической и экспериментальной неврологии, 2020 Introduction. In carriers of a mutation in the lysosomal enzyme glucocerebrosidase (GBA) gene, the risk of Parkinson disease (PD) is increased by 78 times. However, not all carriers of the GBA gene mutations develop PD during their lifetime.
Tatiana S. Usenko +9 more
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Dual-Task Performance in GBA Parkinson’s Disease [PDF]
Parkinson's Disease, 2017 Introduction. Parkinson’s disease patients carrying a heterozygous mutation in the geneglucocerebrosidase(GBA-PD) show faster motor and cognitive decline than idiopathic Parkinson’s disease (iPD) patients, but the mechanisms behind this observation are not well understood. Successful dual tasking (DT) requires a smooth integration of motor and nonmotor
Karin Srulijes +10 more
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Modelling cholinergic and dopaminergic function over time in Parkinson’s disease with and without GBA1 variants [PDF]
npj Parkinson's DiseaseParkinson’s Disease (PD) patients carrying GBA1-variants (GBA-PD) often show a faster cognitive decline, suggesting accelerated cholinergic degeneration.
Sofie Slingerland +10 more
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Civil Aviation High TECHNOLOGIES, 2018 The problem of accurate navigation support for landing systems is of great importance in our time in connection with the constantly increasing intensity of air traffic in major airports. At present, there is a trend towards a transition to navigational identification of aircraft by satellite radio navigation systems.
O. I. Zavalishin
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Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies [PDF]
Nature CommunicationsGBA is the major risk gene for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), two common α-synucleinopathies with cognitive deficits. Here we investigate the role of mutant GBA in cognitive decline by utilizing Gba (L444P) mutant, SNCA ...
D. J. Vidyadhara +6 more
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Neurology Genetics, 2020 To provide a variant-specific estimate of incidence, penetrance, sex distribution, and association with dementia of the 4 most common Parkinson disease (PD)-associated GBA variants, we analyzed a large cohort of 4,923 Italian unrelated patients with primary degenerative parkinsonism (including 3,832 PD) enrolled in a single tertiary care center and 7 ...
Letizia Straniero +13 more
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A Multi-Target Detection Method Based on Improved U-Net for UWB MIMO Through-Wall Radar
Remote Sensing, 2023 Ultra-wideband (UWB) multiple-input multiple-output (MIMO) through-wall radar is widely used in through-wall human target detection for its good penetration characteristics and resolution.
Jun Pan +6 more
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Geosciences, 2022 The reuse of vintage datasets which were acquired in the 20th century can pose challenges for modern geophysical modeling due to missing detailed preprocessing information, significant uncertainties, or lack of precise tracking, etc.
Ingrid Schattauer +4 more
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Biosensors, 2022 In the past twelve years, digital image colorimetry (DIC) on smartphones has acquired great importance as an alternative to the most common analytical techniques.
Pablo Cebrián +5 more
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