Results 21 to 30 of about 25,057 (208)

Gene Expression of Lysosomal Membrane Proteins in Parkinson Disease, Associated with Mutations in the Glucocerebrosidase Gene (GBA)

Анналы клинической и экспериментальной неврологии, 2020
Introduction. In carriers of a mutation in the lysosomal enzyme glucocerebrosidase (GBA) gene, the risk of Parkinson disease (PD) is increased by 78 times. However, not all carriers of the GBA gene mutations develop PD during their lifetime.
Tatiana S. Usenko, Anastasia I. Bezrukova, Darya A. Bogdanova, Mikhail A. Nikolaev, Irina V. Miliukhina, Elizaveta V. Gracheva, Konstantin A. Senkevich, Ekaterina Yu. Zakharova, Anton K. Emelyanov, Sofya N. Pchelina   +9 more
doaj   +1 more source

Three-Dimensional Motion Compensation Method Based on Sparse Array Designed for Time-Division Multiplexing Multiple-Input-Multiple-Output Through-Wall Radar

Applied Sciences, 2023
A large-aperture radar composed of a multiple-input-multiple-output (MIMO) planar array can complete 3D through-wall imaging (TWI), but the simultaneous work of the multiple transceiver channels leads to difficulties in designing the hardware.
Jun Pan, Xiao Liang, Shiyou Wu, Di Zhao, Kun Yan, Jinliang Nie, Jianmin Hu, Bin Zhou, Guangyou Fang   +8 more
doaj   +1 more source

Solving Color Reproducibility between Digital Devices: A Robust Approach of Smartphones Color Management for Chemical (Bio)Sensors

Biosensors, 2022
In the past twelve years, digital image colorimetry (DIC) on smartphones has acquired great importance as an alternative to the most common analytical techniques.
Pablo Cebrián, Leticia Pérez-Sienes, Isabel Sanz-Vicente, Ángel López-Molinero, Susana de Marcos, Javier Galbán   +5 more
doaj   +1 more source

INTEGRATED GENOMIC ANALYSIS OF ISOLATED CD14+ MONOCYTES IN PATIENTS WITH GBA-RELATED PARKINSON¿S DISEASE [PDF]

, 2021
Background: Genetic mutations of the gene encoding for the beta- glucocerebrosidase (GCase), GBA gene, represent the major genetic risk factor for Parkinson’s disease (PD).
RIBOLDI, GIULIETTA
core   +1 more source

Parkinson disease and STN-DBS: cognitive effects in GBA mutation carriers [PDF]

, 2022
OBJECTIVE: To compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and non-carriers with and without subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD).
Liu, Y, Link, S, Marder, KS, Verhagen, L, Goetz, CG, Mouradian, MM, Wilson, R, Afshari, M, Garcia, P, Mangone, G, Aasly, J, Shanker, V, Stebbins, G, Bressman, S, Welter, M-L, Bernard, B, Saunders-Pullman, R, Hill, EJ, Corvol, J-C, Ehrlich, D, Alcalay, RN, Nichols, WC, Pal, G, Anderson, S, Rosenbaum, M, Ouyang, B, Lythe, V, Foltynie, T, de Bie, RMA, Hall, D, Sani, S   +30 more
core   +1 more source

Cognitive Functioning of Glucocerebrosidase (GBA) Non-manifesting Carriers

Frontiers in Neurology, 2021
Mutations and variants in the glucocerebrosidase (GBA) gene are among the most common genetic risk factors for the development of Parkinson's disease (PD).
Eileen E. Moran, Eileen E. Moran, Susan B. Bressman, Susan B. Bressman, Roberto A. Ortega, Roberto A. Ortega, Deborah Raymond, Deborah Raymond, William C. Nichols, Christina A. Palmese, Christina A. Palmese, Sonya Elango, Sonya Elango, Matthew Swan, Matthew Swan, Vicki Shanker, Vicki Shanker, Imali Perera, Cuiling Wang, Molly E. Zimmerman, Rachel Saunders-Pullman, Rachel Saunders-Pullman   +21 more
doaj   +1 more source

Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2

Molecular Brain, 2021
Lysosomal dysfunction is a central pathway associated with Parkinson’s disease (PD) pathogenesis. Haploinsufficiency of the lysosomal hydrolase GBA (encoding glucocerebrosidase (GCase)) is one of the largest genetic risk factors for developing PD ...
Ria Thomas, Elizabeth B. Moloney, Zachary K. Macbain, Penelope J. Hallett, Ole Isacson   +4 more
doaj   +1 more source

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein. [PDF]

PLoS Genetics, 2015
Homozygous mutations in the glucocerebrosidase (GBA) gene result in Gaucher disease (GD), the most common lysosomal storage disease. Recent genetic studies have revealed that GBA mutations confer a strong risk for sporadic Parkinson's disease (PD).
Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi   +12 more
doaj   +1 more source

Indonesian EFL teachers

Journal on English as a Foreign Language, 2023
Many studies indicated a genre-based approach (GBA) as an effective method in English foreign language (EFL) teaching and GBA is also integrated into the English teaching curriculum.
Nurfadilah Nadjib, Anita Triastuti
doaj   +1 more source

gba TOPO clone sequences

, 2022
gba TOPO clone ...
Blake Carrington (13863692)
core   +1 more source