Results 101 to 110 of about 3,043 (176)

Genetic Associations of Parkinson's Disease Clinical, Pathological, and Data-Driven Subtypes. [PDF]

Genes (Basel)
Negida A, Abouelmagd ME, Hamed BM, Hawas Y, Dziri A, Negida Y, Berman BD, Barrett MJ.   +7 more
europepmc   +1 more source

Family studies in Gaucher Disease: a key resource for early diagnosis and personalized treatment strategies. [PDF]

Orphanet J Rare Dis
Vinci M, Giacomarra M, D'Errico A, Fischetto R, Palumbo G, Tartaglione I, Tirelli P, Messina E, Russo M, Francofonte D, Colomba P, Duro G, Zizzo C.   +12 more
europepmc   +1 more source

Large-scale genetic characterization of Parkinson's disease in the African and African admixed populations. [PDF]

Brain
Akçimen F, Paquette K, Wild Crea P, Step K, Waldo E, Koretsky MJ, Saffie-Awad P, Achoru C, Taiwo F, Ozomma S, Onwuegbuzie G, Khani M, Grant S, Owolabi L, Okereke C, Oshinaike O, Iwuozo E, Akerman SC, Lee PS, Oyakhire S, Osemwegie N, Daida K, Abubakar S, Olusanya A, Isayan M, Alvarez C, Traurig R, Ogunmodede A, Samuel S, Makarious MB, Sa'ad F, Olanigan R, Levine K, Ogbimi EM, Vitale D, Odiase F, Ojini F, Odeniyi O, Fang ZH, Obianozie N, Hall DA, Nwazor E, Xie T, Nwaokorie F, Padmanaban M, Nwani P, Shamim EA, Nnama A, Standaert D, Komolafe M, Dean M, Osaigbovo G, Disbrow E, Ishola I, Rawls A, Imarhiagbe F, Chandra S, Erameh C, Hinson V, Louie N, Idowu A, Solle J, Norris SA, Ibrahim A, Kilbane C, Sukumar G, Shulman LM, Ezuduemoih D, Staisch J, Breaux S, Dalgard C, Foster ER, Bello A, Ameri A, Real R, Ikwenu E, Morris HR, Anyanwu R, Furr Stimming E, Billingsley K, Alaofin W, Alvarez Jerez P, Agabi O, Hernandez DG, Akinyemi R, Arepalli S, Malik L, Owolabi R, Nyandaiti Y, Leonard HL, Wahab K, Abiodun O, Hernandez CF, Abdulai F, Iwaki H, Bardien S, Klein C, Hardy J, Houlden H, Galvelis KG, Nalls MA, Dahodwala N, Aamodt W, Hill E, Espay A, Factor S, Branson C, Blauwendraat C, Singleton AB, Ojo O, Chahine LM, Okubadejo N, Bandres-Ciga S.   +112 more
europepmc   +1 more source

148 | Lysosomal and synuclein pathology in ipsc-derived dopaminergic neurons from gba1-mutant parkinson’s disease patients

Journal of Biological Research
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is marked by a progressive decline in motor function resulting from the loss of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of α ...
Società Italiana di Biologia Sperimentale
doaj  

APOE, Aβ42, and tau differentially impact cognitive decline in Sporadic, GBA1 and LRRK2 Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Botta R, Locascio JJ, Ye R, Goodheart AE, Gomperts SN.   +4 more
europepmc   +1 more source

Protocol of ASPro-PD: a phase 3 trial of ambroxol to slow progression in genetically stratified Parkinson's disease. [PDF]

J Neurol
Toffoli M, Menozzi E, Cullen M, Chowdhury K, Ahmed S, Freemantle N, Duffen J, Wyse RK, Stott SRW, Matthews H, Dexter D, Ikeji F, Moss J, Watts P, Foltynie T, Kieburtz K, Rascol O, Poewe W, Schapira AHV.   +18 more
europepmc   +1 more source

Synuclein Disorder-Related Genetic Determinants of Mild Behavioural Impairment in a Pre-Clinical Community Cohort. [PDF]

Int J Geriatr Psychiatry
Sander-Long M, Creese B, Corbett A, Rosenzweig I, Cummings J, Ballard C.   +5 more
europepmc   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers. [PDF]

Mov Disord
Agin-Liebes J, Haimovich A, Griep R, Hatcher NG, Yao L, Waters C, Padmanabhan S, Alcalay RN.   +7 more
europepmc   +1 more source

The interplay between GBA1 status and age of onset on cognitive, motor and non-motor outcomes in Parkinson's disease: multicenter cross-sectional study. [PDF]

J Neurol
Ledda C, Gallo S, Avenali M, Artusi CA, Imbalzano G, Donetto F, Montanaro E, Romagnolo A, Mitrotti P, Gallo L, De Micco R, Sant'Elia V, Siciliano M, Tessitore A, Calandra-Buonaura G, Giannini G, Sambati L, Lopiano L, Valente EM, Bozzali M.   +19 more
europepmc   +1 more source

Clinical and Biological Determinants of Longitudinal Cognitive Function in Patients With GBA1 Variants and Subthalamic Deep Brain Stimulation. [PDF]

Ann Neurol
Loeffler MA, Klocke P, Wurster I, Lerche S, Cebi I, Gasser T, Gharabaghi A, Brockmann K, Weiss D.   +8 more
europepmc   +1 more source