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Development of Monoclonal Antibodies Against GBF1 and Their Use in Studying Its Functions

Journal of Interferon & Cytokine Research, 2005
Interferon-gamma (IFN-gamma) regulates a number of cellular genes using a variety of cellular signaling pathways. Previously, we identified a novel IFN-regulated element, IFN-gamma-activated transcriptional element (GATE), in the promoter of the murine IFN regulatory factor-9 (IRF-9) gene. This element binds to novel factors.
Sanjit K, Roy +5 more
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A Molecular Mechanism for GBF1 Recruitment to cis-Golgi Membranes

2017
ADP-ribosylation factors (Arfs) play a central role in the regulation of vesicular trafficking through the Golgi. Arfs are activated on cis-Golgi membranes exclusively by the guanine nucleotide exchange factor (GEF) Golgi-specific BFA resistance factor 1 (GBF1), upon recruitment from cytosol. Membrane association of Arf is essential for its activation;
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Characterization of the GBF1-Arf1 axis in enterovirus RNA replication

The Enterovirus genus includes many known and emerging pathogens, such as poliovirus, enteroviruses A71 and D68, rhinoviruses, and others. Enterovirus infection induces the massive remodeling of intracellular membranes and the development of specialized domains harboring viral replication complexes, called replication organelles.
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Evolutionary origin and functional diversification of plant GBF1-type ARF guanine-nucleotide exchange factors