Results 1 to 10 of about 214,335 (315)
Cell Stress, 2021 Cellular adaptation to stress is a crucial homeostatic process for survival, metabolism, physiology, and disease. Cells respond to stress stimuli (e.g., nutrient starvation, growth factor deprivation, hypoxia, low energy, etc.) by changing the activity ...
Constantinos Demetriades +2 more
doaj +1 more source
Src activates retrograde membrane traffic through phosphorylation of GBF1
eLife, 2021 The Src tyrosine kinase controls cancer-critical protein glycosylation through Golgi to ER relocation of GALNTs enzymes. How Src induces this trafficking event is unknown.
Joanne Chia +8 more
doaj +1 more source
Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster [PDF]
Open Biology, 2017 Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is
Stefano Sechi +8 more
doaj +1 more source
Cdc42 regulates cytokine expression and trafficking in bronchial epithelial cells
Frontiers in Immunology, 2022 Airway epithelial cells can respond to incoming pathogens, allergens and stimulants through the secretion of cytokines and chemokines. These pro-inflammatory mediators activate inflammatory signaling cascades that allow a robust immune response to be ...
Rowayna Shouib, Gary Eitzen
doaj +1 more source
Alzheimer’s Research & Therapy, 2020 Background Preventing dementia onset is one of the global public health priorities: around 35% of dementia cases could be attributable to modifiable risk factors.
Elena Rolandi +6 more
doaj +1 more source
Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles
Microbial Cell, 2022 Members of the family of oxysterol-binding proteins mediate non-vesicular lipid transport between membranes and contribute to longevity in different manners.
Ilham Kadhim +4 more
doaj +1 more source
Diverse roles for the p24 family of proteins in eukaryotic cells
Biomolecular Concepts, 2012 Members of the p24 protein family form a highly conserved family of type I transmembrane proteins that are abundant components of the early secretory pathway.
Schuiki Irmgard, Volchuk Allen
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Polytopic cargo proteins are synthesized and exported along the secretory pathway from the endoplasmic reticulum (ER), through the Golgi apparatus, with eventual insertion into the plasma membrane (PM).
Timothy Angelotti
doaj +1 more source
Frontiers in Molecular Neuroscience, 2019 The calmodulin (CaM)-like Ca2+-sensor proteins caldendrin, calneuron-1 and -2 are members of the neuronal calcium-binding protein (nCaBP)-family, a family that evolved relatively late during vertebrate evolution.
Jennifer Mundhenk +3 more
doaj +1 more source
Golgi Apparatus: A Potential Therapeutic Target for Autophagy-Associated Neurological Diseases
Frontiers in Cell and Developmental Biology, 2020 Autophagy has dual effects in human diseases: appropriate autophagy may protect cells from stress, while excessive autophagy may cause cell death. Additionally, close interactions exist between autophagy and the Golgi.
Shuwen Deng, Jia Liu, Xiaomei Wu, Wei Lu
doaj +1 more source