Results 31 to 40 of about 33,572 (265)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Identification of Group B Streptococcus Serotypes and Genotypes in Late Pregnant Women and Neonates That Are Associated With Neonatal Early-Onset Infection in a South China Population

Frontiers in Pediatrics, 2020
Background: Group B streptococcus (GBS) colonized in late pregnancies has been associated with neonatal early-onset GBS disease (GBS-EOD) in China.Objective: This study investigated if GBS serotype and genotype in late pregnancy is associated with GBS ...
Zhu Yao, Wu Jiayin, Zheng Xinyi, Chen Ling, He Mingyuan, Ma Simin, Lin Yayin, Lin Xinzhu, Chen Chao   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Neutrosophic gb-closed Sets and Neutrosophic gb-Continuity

Neutrosophic Sets and Systems, 2019
Smarandache introduced and developed the new concept of Neutrosophic set from the Intuitionistic fuzzy sets. A.A. Salama introduced Neutrosophic topological spaces by using the Neutrosophic crisp sets. Aim of this paper is we introduce and study the concepts Neutrosophic generalized b closed sets and Neutrosophic generalized b continuity in ...
C.Maheswari, S. Chandrasekar
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Association of sexually-transmitted infection and African–American race with Streptococcus agalactiae colonization in pregnancy

Antimicrobial Resistance and Infection Control, 2020
Background Group B Streptococcus (GBS) remains a significant cause of neonatal infection, but the maternal risk factors for GBS colonization remain poorly defined.
Gerald A. Capraro, Sajel Lala, Khaldia Khaled, Elizabeth Gosciniak, Brianna Saadat, Sarah M. Alvarez, Seema Kumar, Tara Calhoun, Edward Landry, Gloria Caldito, Joseph A. Bocchini, John A. Vanchiere   +11 more
doaj   +1 more source

Group B Streptococcus CAMP Factor Does Not Contribute to Interactions with the Vaginal Epithelium and Is Dispensable for Vaginal Colonization in Mice

Microbiology Spectrum, 2021
The Gram-positive pathogen group B Streptococcus (GBS) is a leading cause of neonatal bacterial infections, preterm birth, and stillbirth. Although maternal GBS vaginal colonization is a risk factor for GBS-associated adverse birth outcomes, mechanisms ...
Mallory B. Ballard, Vicki Mercado-Evans, Madelynn G. Marunde, Hephzibah Nwanosike, Jacob Zulk, Kathryn A. Patras   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Prevalence of group B streptococcus colonization in pregnant women in a tertiary care center in Korea [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveThe purpose of this study was to evaluate the group B streptococcus (GBS) colonization rate in pregnant Korean women using selective culture media for GBS and to identify obstetrical complications and GBS-induced early-onset neonatal sepsis ...
Da Hyun Kim, Byoung Jin Min, Eun Jung Jung, Jung Mi Byun, Dae Hoon Jeong, Kyung Bok Lee, Moon Su Sung, Ki Tae Kim, Young Nam Kim   +8 more
doaj   +1 more source