Results 31 to 40 of about 983,517 (240)

The Philosophical Base of Urdu Ghazal: An Impression

open access: yesبازیافت, 2018
Literature provides a way for understanding life in the perspective ofman, society and universe. Poets in poetry as it is said reunite themselves on the basis of their existence. This attitude brings them near to the state of philosophy.
Rabia Rizvi, Sadat Hasan Saeed
doaj   +3 more sources

Khalid Ahmad's Contribution in Mythical Poetry

open access: yesمجلہ تحقیق, 2020
Myth is a folklore genre consisting of narratives that play a fundamental role in a society. World literature is full of these foundational tales. Urdu literature is also fully diluted with these tales. The main characters in myths are usually non-humans,
Shabnam Ishaq, Zaheer Hasan Watto
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Development of Microbial Biofilms and Their Role in device, non-device and organ system level Infections

open access: yesBioscientific Review
Background. Microorganisms, while providing many health benefits to human beings and other living organisms, are also responsible for significant infections. They cause infections in both planktonic and biofilm modes.
Farah Liaqat   +6 more
doaj   +1 more source

Steel Augmented Production Function: Robust Analysis for European Union [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2017
This study contributes to the empirical literature on augmented neo-classical production function. It is done by introducing steel production into macro-production function of the European Union.
Bilal Mehmood   +2 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Simultaneous RP-HPLC determination of sparfloxacin and dexamethasone in pharmaceutical formulations

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
The present study describes the development and subsequent validation of simple and accurate stability indicating RP-HPLC method for the determination of sparfloxacin and dexamethasone in pharmaceutical formulations in the presence of their stress ...
Syed Naeem Razzaq   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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