Results 31 to 40 of about 606,031 (228)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Urdu Ghazal: The Imbibition of Arabic & Persian Themes

بازیافت, 2017
Literature is an appropriate mode for expression of thought andvision. Poetry is its most impressive and effective form of  communication. It is the most beautiful and sensitive source to expresses the feelings, mood and experiences of the poet.
Farzana Riaz, Babar Naseem Aasi
doaj   +3 more sources

Steel Augmented Production Function: Robust Analysis for European Union [PDF]

Statistika: Statistics and Economy Journal, 2017
This study contributes to the empirical literature on augmented neo-classical production function. It is done by introducing steel production into macro-production function of the European Union.
Bilal Mehmood, Muhammad Aleem, Marwah Rafaqat   +2 more
doaj  

BARCHAN: Blob Alignment for Robust CHromatographic ANalysis

, 2017
Comprehensive Two dimensional gas chromatography (GCxGC) plays a central role into the elucidation of complex samples. The automation of the identification of peak areas is of prime interest to obtain a fast and repeatable analysis of chromatograms.
Couprie, Camille, Duval, Laurent, Hénon, Sophie, Moreaud, Maxime, Souchon, Vincent, Tebib, Mélinda   +5 more
core   +3 more sources

Decays of Non-strange Negative Parity Baryons in the 1/Nc Expansion [PDF]

, 2004
The decays of non-strange negative parity baryons via the emission of single $\pi$ and $\eta$ mesons are analyzed in the framework of the $1/N_c$ expansion.
C. Schat, D. Faiman, D. Pirjol, J. L. Goity, N. N. Scoccola   +4 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Multiple-charge transfer and trapping in DNA dimers

, 2010
We investigate the charge transfer characteristics of one and two excess charges in a DNA base-pair dimer using a model Hamiltonian approach. The electron part comprises diagonal and off-diagonal Coulomb matrix elements such a correlated hopping and the ...
A. Nitzan, D. DeVault, E. Starikov, Frithjof B. Anders, G. Schuster, Gertrud Zwicknagl, R. Bulla, Ralf Bulla, Sabine Tornow, T. Chakraboty, U. Weiss   +10 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Research investigating individual device preference and e-learning quality perception: can a one-solution-fits-all e-learning solution work?

Heliyon, 2021
Background: COVID-19 caused a paradigm shift for educators, and raised many questions about the future of technology in the delivery of educational content.
Samnan Ali, Stephen R. Gulliver, M. Amaad Uppal, Muhammad Basir   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source