Metabolomics Benefits from Orbitrap GC–MS—Comparison of Low- and High-Resolution GC–MS [PDF]
The development of improved mass spectrometers and supporting computational tools is expected to enable the rapid annotation of whole metabolomes. Essential for the progress is the identification of strengths and weaknesses of novel instrumentation in direct comparison to previous instruments.
Daniel Stettin+2 more
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Determination of propofol by GC/MS and fast GC/MS-TOF in two cases of poisoning [PDF]
Two cases of suspected acute and lethal intoxication caused by propofol were delivered by the judicial authority to the Department of Sciences for Health Promotion and Mother-Child Care in Palermo, Sicily.
Argo A.+8 more
core +4 more sources
Enzymatic digestion and selective quantification of underivatised [delta]9-tetrahydrocannabinol and cocaine in human hair using gas chromatography-mass spectrometry. [PDF]
Gas chromatography-mass spectrometric (GC-MS) methods for drug analysis routinely employ derivatising reagents. The aim of this paper was to develop a method for the analysis of two recreational drugs, delta-9-tetrahydrocannabinol ([delta](9)-THC) and ...
Barker, James+3 more
core +3 more sources
A TGA/FTIR and Mass Spectral Study on the Thermal Degradation of Bisphenol A Polycarbonate [PDF]
The thermal degradation of polycarbonate under nitrogen was studied using TGA/FTIR, GC/MS and LC/MS as a function of mass loss. The gases evolved during degradation were inspected by in situ FTIR and then the evolved products were collected and analysed ...
Jang, Bok Nam, Wilkie, Charles A.
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GC/MS and the chromatographic challenge
Application of high pressure drop (narrow-bore, vacuum-outlet) columns shortens analysis times and lowers detection limits at least in proportion to the reduced column diameter. In the scanning mode in GC/MS, only quadrupole instruments can meet this challenge for columns (with 105 plates I with diameters down to 30-50 mum. For still faster separations
P.A. Leclercq, C.A.M.G. Cramers
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Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]
Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb+45 more
core +1 more source
Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct 'on spot' derivatization [PDF]
The objective of this study was the development of an accurate and sensitive method for the determination of gamma-hydroxybutyric acid (GHB) in dried whole blood samples using a GC-MS method.
Ingels, Ann-Sofie+2 more
core +1 more source
Development and validation of a GC-MS method for the detection and quantification of clotiapine in blood and urine specimens and application to a postmortem case [PDF]
INTRODUCTION: Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients.
Busardo', FRANCESCO PAOLO+5 more
core +5 more sources
Fundamentals of Integrated GC-MS. Part III: The Integrated GC-MS Analytical System. By B. J. Gudwinowicz, M. J. Gudwinowicz and H. F. Martin. Pp. vii + 603. (Dekker: New York and Basel, 1977.) SFr.190.
openaire +2 more sources
Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS [PDF]
Components of 50% ethanolic chamomile (Matricaria recutica L.) flower extract, previously found antibacterial in a TLC-bioautographic study, were separated and isolated by the use of on-line OPLC, which consisted of an OPLC 50 BS system, an on-line ...
Héthelyi, Éva B.+5 more
core +1 more source