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Metabolomics Benefits from Orbitrap GC–MS—Comparison of Low- and High-Resolution GC–MS [PDF]

open access: yesMetabolites, 2020
The development of improved mass spectrometers and supporting computational tools is expected to enable the rapid annotation of whole metabolomes. Essential for the progress is the identification of strengths and weaknesses of novel instrumentation in direct comparison to previous instruments.
Daniel Stettin   +2 more
openaire   +4 more sources

Determination of propofol by GC/MS and fast GC/MS-TOF in two cases of poisoning [PDF]

open access: yesJournal of Analytical Toxicology, 2017
Two cases of suspected acute and lethal intoxication caused by propofol were delivered by the judicial authority to the Department of Sciences for Health Promotion and Mother-Child Care in Palermo, Sicily.
Argo A.   +8 more
core   +4 more sources

Enzymatic digestion and selective quantification of underivatised [delta]9-tetrahydrocannabinol and cocaine in human hair using gas chromatography-mass spectrometry. [PDF]

open access: yes, 2012
Gas chromatography-mass spectrometric (GC-MS) methods for drug analysis routinely employ derivatising reagents. The aim of this paper was to develop a method for the analysis of two recreational drugs, delta-9-tetrahydrocannabinol ([delta](9)-THC) and ...
Barker, James   +3 more
core   +3 more sources

A TGA/FTIR and Mass Spectral Study on the Thermal Degradation of Bisphenol A Polycarbonate [PDF]

open access: yes, 2004
The thermal degradation of polycarbonate under nitrogen was studied using TGA/FTIR, GC/MS and LC/MS as a function of mass loss. The gases evolved during degradation were inspected by in situ FTIR and then the evolved products were collected and analysed ...
Jang, Bok Nam, Wilkie, Charles A.
core   +2 more sources

GC/MS and the chromatographic challenge

open access: yesJournal of High Resolution Chromatography, 1988
Application of high pressure drop (narrow-bore, vacuum-outlet) columns shortens analysis times and lowers detection limits at least in proportion to the reduced column diameter. In the scanning mode in GC/MS, only quadrupole instruments can meet this challenge for columns (with 105 plates I with diameters down to 30-50 mum. For still faster separations
P.A. Leclercq, C.A.M.G. Cramers
openaire   +3 more sources

Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]

open access: yes, 2018
Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb   +45 more
core   +1 more source

Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct 'on spot' derivatization [PDF]

open access: yes, 2010
The objective of this study was the development of an accurate and sensitive method for the determination of gamma-hydroxybutyric acid (GHB) in dried whole blood samples using a GC-MS method.
Ingels, Ann-Sofie   +2 more
core   +1 more source

Development and validation of a GC-MS method for the detection and quantification of clotiapine in blood and urine specimens and application to a postmortem case [PDF]

open access: yes, 2015
INTRODUCTION: Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients.
Busardo', FRANCESCO PAOLO   +5 more
core   +5 more sources

GC-MS system [PDF]

open access: yesNature, 1977
Fundamentals of Integrated GC-MS. Part III: The Integrated GC-MS Analytical System. By B. J. Gudwinowicz, M. J. Gudwinowicz and H. F. Martin. Pp. vii + 603. (Dekker: New York and Basel, 1977.) SFr.190.
openaire   +2 more sources

Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS [PDF]

open access: yes, 2012
Components of 50% ethanolic chamomile (Matricaria recutica L.) flower extract, previously found antibacterial in a TLC-bioautographic study, were separated and isolated by the use of on-line OPLC, which consisted of an OPLC 50 BS system, an on-line ...
Héthelyi, Éva B.   +5 more
core   +1 more source

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