Results 81 to 90 of about 1,425,145 (305)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density and telomere-specific effects [PDF]

, 2005
This study presents the first global, 1 Mbp level analysis of patterns of nucleotide substitutions along the human lineage. The study is based on the analysis of a large amount of repetitive elements deposited into the human genome since the mammalian ...
Arndt, Peter F, Hwa, Terence, Petrov, Dmitri A   +2 more
core  

Metal-poor hypervelocity star candidates from the Sloan Digital Sky Survey

, 2011
Hypervelocity stars are believed to be ejected out from the Galactic center through dynamical interactions of (binary) stars with the central massive black hole(s).
Abadi, Bartko, Blaauw, Bromley, Brown, Brown, Dong, Edelmann, Gnedin, Gould, Ivezić, Kenyon, Kiziltan, Kollmeier, Kollmeier, Koposov, Lee, Lu, Lu, Merritt, Munn, Perets, Perets, Poveda, Rastegaev, Sesana, Teyssier, Williams, Xue, York, Yu, Zhang   +31 more
core   +1 more source

A comparison of GC-FID and PTR-MS toluene measurements in ambient air under conditions of enhanced monoterpene loading [PDF]

, 2010
Toluene was measured using both a gas chromatographic system (GC), with a flame ionization detector (FID), and a proton transfer reaction-mass spectrometer (PTR-MS) at the AIRMAP atmospheric monitoring station Thompson Farm (THF) in rural Durham, NH ...
Ambrose, Jesse L., Frinak, E. K., Haase, K., Jordan, C., Mayne, Howard R., Russo, R. S., Sive, B. C., Talbot, Robert W., White, M. L., Zhou, Y.   +9 more
core   +4 more sources

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Key Aroma Differences in Volatile Compounds of Aged Feng-Flavored Baijiu Determined Using Sensory Descriptive Analysis and GC×GC–TOFMS

Foods
Sensory descriptive analysis of aged feng-flavored Baijiu liquor indicated notable differences in samples of different ages. The samples of freshly distilled Baijiu and those with shorter storage times exhibit bran and fresh green flavors, whereas, with ...
Jinmei Ren, Zhijian Li, Wei Jia
doaj   +1 more source

The role of diet and other environmental factors in the causation of gastric cancer in Iran—A population based study [PDF]

Despite a declining trend in the incidence of gastric cancer (GC), it is still a major global public health concern of the 21st century. The rates of GC reported from Ardabil Province, Iran, are among the highest in the world.
Acquavella, Aragones, Blackburn, Blair, Boeing, Boeing, Buiatti, Burns, Chen, Chow, Correa, Correa, Correa, Crew, Danesh, De Stefani, De Stefani, De Stefani, De Stefani, Derakhshan, Dorant, Dorzhgotov, Drake, Ekstrom, Engel, Eslick, Ferlay, Forman, Forman, Fox, Galanis, Gao, Goldbohm, Gonzalez, Gonzalez, Haenszel, Hamada, Harrison, Helicobacter and Cancer Collaborative Group, Honda, Howard, Huang, IARC, IARC, IARC, Inoue, Ito, Jansen, Joossens, Kamineni, Karmali, Kim, Kinlen, La Vecchia, La Vecchia, Lauren, Lee, Lissowska, Lissowska, Lopez-Carrillo, Machida-Montani, Mathew, Munoz, Munoz, Nomura, Palli, Parent, Parkin, Parsonnet, Rao, Rigdon, Rocco, Sadjadi, Sadjadi, Sadjadi, Samadi, Sitas, Takezaki, Touati, Tsugane, Uemura, Vineis, Ward, Watanabe, World Cancer Research Fund, American Institute for Cancer Research, Xue, Yatsuya, Yazdanbod, You   +88 more
core   +1 more source

Seasonal Variation of Essential Oil Yield and Composition of Sage (Salvia officinalis L.) Grown in Castilla - La Mancha (Central Spain) [PDF]

, 2012
Links between phenology, yield and composition of the essential oil of common sage, Salvia officinalis L., grown in Guadalajara (Central Spain) were determined in the different phases of the biological cycle during one year.
Arrabal Miguel, Carlos, Arraiza Bermudez-Cañete, Maria Paz, López, José V.   +2 more
core   +3 more sources

GcDUO: an open-source software for GC × GC–MS data analysis

Briefings in Bioinformatics
Abstract Comprehensive 2D gas chromatography coupled with mass spectrometry (GC × GC–MS) is a powerful analytical technique. However, the complexity and volume of data generated pose significant challenges for data processing and interpretation, limiting a broader adoption.
Llambrich, Maria, van der Kloet, Frans M, Sementé, Lluc, Rodrigues, Anaïs, Samanipour, Saer, Stefanuto, Pierre-Hugues, Westerhuis, Johan A, Cumeras, Raquel, Brezmes, Jesús   +8 more
openaire   +2 more sources

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source