Results 101 to 110 of about 14,720 (176)

Bringing precision medicine to the management of pregnancy in women with glucokinase-MODY: a study of diagnostic accuracy and feasibility of non-invasive prenatal testing. [PDF]

, 2023
AIMS/HYPOTHESIS: In pregnancies where the mother has glucokinase-MODY (GCK-MODY), fetal growth is determined by fetal genotype. When the fetus inherits a maternal pathogenic GCK variant, normal fetal growth is anticipated, and insulin treatment of ...
SE Flanagan (21320006), AJ Chakera (21481802), B Bunce (21854630), JAL Houghton (21905453), MH Shepherd (11760215), AE Hughes (14500538), G Spyer (21956381), AT Hattersley (7655273)   +7 more
core  

Çocukluk Çağında Diyabetin Nadir Bir Nedeni: Glukokinaz Mutasyonu (MODY2)

Turkish Journal of Family Practice, 2014
Gençlikte Ortaya Çıkan Erişkin Tip Diyabet [Maturity-Onset Diabetes of the Young (MODY)] monogenik olarak kalıtılan, beta hücre fonksiyon kaybına ikincil ortaya çıkan nadir bir diyabet tipidir.
Hale Ünver Tuhan, Ahmet Anık, Gönül Çatlı, Sefa Kızıldağ, Ayhan Abacı, Ece Böber   +5 more
doaj  

Letter to the Editor: Stress Hyperglycemia or Glucokinase Maturity Onset Diabetes of the Young (GCK-MODY) or Both? [PDF]

Clin Pediatr Endocrinol, 2023
Doherty-Kirby A.
europepmc   +1 more source

Genetics MODY diabetes

, 2012
The most common form of monogenic diabetes is MODY (Maturity-Onset Diabetes of the Young). It ranks among genetic defects of the β cell. It is clinically heterogenous group of disorders characterised with non insulin-dependent diabetes mellitus with ...
Dušátková, Petra
core  

Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations

, 2010
Glucokinase diabetes, also called GCK-MODY or maturity-onset diabetes of the young type 2 (MODY2), is caused by heterozygous mutations in the gene encoding glucokinase (GCK).
Pruhova, Stepanka, Kolouskova, Stanislava, Pedersen, Oluf, Lebl, Jan, Hansen, Torben, Cinek, Ondrej, Dusatkova, Petra, Sumnik, Zdenek, Jan Lebl, Zdenek Sumnik, Oluf Pedersen, Ondrej Cinek, Stanislava Kolouskova, Petra Dusatkova, Stepanka Pruhova, Torben Hansen   +15 more
core   +1 more source

High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.

, 2011
OBJECTIVE: Maturity-onset diabetes of the young (MODY) as a result of mutations in hepatocyte nuclear factor 1-α (HNF1A) is often misdiagnosed as type 1 diabetes or type 2 diabetes.
Jane Lawry, Katharine R. Owen, Hattersley, Andrew T., Gloyn, A. L., Tim J. McDonald, Anna L. Gloyn, Lawry, J., Shields, Beverley, Sian Ellard, Owen, K., Beverley M. Shields, Ellard, Sian, Andrew T. Hattersley, McDonald, Timothy J.   +13 more
core   +1 more source

Cost Effectiveness of GCK-MODY Genetic Screening for Selected Individuals Referred to the Diabetes Prevention Programme

MODY accounts for 1 5% of diabetes cases, of these GCK-MODY comprises approximately 30%.GCKMODY is associated with minimal risk of complications. Efficiently diagnosing GCK-MODY leads to more appropriate management and resource allocation.
Noble, Jane, Ng, N., Lockhart, M., Divilly, P.   +3 more
core  

A review of maturity onset diabetes of the young (MODY) and challenges in the management of glucokinase-MODY

, 2016
• Maturity onset diabetes of the young (MODY), the most common monogenic form of diabetes, accounts for 1–2% of all diabetes diagnoses. • Glucokinase (GCK)-MODY (also referred to as MODY2) constitutes 10–60% of all MODY cases and is inherited as an ...
Jerry R Greenfield, Ramy H Bishay, Greenfield, Jerry R., Bishay, Ramy H. (R19286)   +3 more
core   +1 more source

Asian MODY: are we missing an important diagnosis?

, 2006
AIMS: Maturity onset diabetes of the young (MODY) is a monogenic form of diabetes where correct diagnosis alters treatment, prognosis and genetic counselling. The first UK survey of childhood MODY identified 20 White, but no Asian children with MODY.
Hattersley, AT, Porter, JR, Plunkett, M, Rangasami, JJ, Edwards, J, Gloyn, AL, Barrett, Timothy; id_orcid, Shaw, Nicholas, Shields, BM, Anderson, Janet, Ellard, S, Frayling, TM   +11 more
core   +1 more source

Atypical phenotype associated with reported GCK exon 10 deletions: Clinical judgement is needed alongside appropriate genetic investigations.

, 2016
BACKGROUND: Maturity-onset diabetes of the young (MODY) caused by heterozygous mutations in the glucokinase (GCK) gene typically presents with lifelong, stable, mild fasting hyperglycaemia.

core   +1 more source