Results 1 to 10 of about 23,263 (212)
Targeted sequencing identifies novel variants in common and rare MODY genes
Molecular Genetics & Genomic Medicine, 2019 Background Maturity‐onset diabetes of the young (MODY) is a form of monogenic diabetes with autosomal dominant inheritance. To date, mutations in 11 genes have been frequently associated with this phenotype.
Milena Teles +2 more
exaly +2 more sources
Prevalence of Retinopathy in Adult Patients with GCK-MODY and HNF1A-MODY
Experimental and Clinical Endocrinology and Diabetes, 2015 We aimed to assess the prevalence of diabetic retinopathy (DR) in adult patients with GCK-MODY and HNF1A-MODY in Poland and to identify biochemical and clinical risk factors associated with its occurrence.We examined 74 GCK mutation carriers, 51 with diabetes and 23 with prediabetes, respectively, and 63 patients with HNF1A-MODY.
Bartlomiej Matejko +2 more
exaly +4 more sources
Lipid profile indices in young people with GCK-MODY and HNF1A-MODY
Атеросклероз, 2022 Despite the fact that most young patients with hyperglycemia are diagnosed with type 1 (T1DM) and type 2 (T2DM) diabetes, up to 10 % of all cases of the disease are MODY diabetes.
Alla K. Ovsyannikova +3 more
doaj +1 more source
Archives of Endocrinology and Metabolism, 2022 Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM).
Özlem Üstay +10 more
doaj +1 more source
Precision diabetes: Lessons learned from maturity‐onset diabetes of the young (MODY)
Journal of Diabetes Investigation, 2022 Maturity‐onset of diabetes of the young (MODY) are monogenic forms of diabetes characterized by early onset diabetes with autosomal dominant inheritance.
Mustafa Tosur, Louis H Philipson
doaj +1 more source
Chinese Medical Journal, 2023 . Background:. Maturity-onset diabetes of the young (MODY) is the most common monogenic diabetes. The aim of this study was to assess the prevalence of MODY in phenotypic type 2 diabetes (T2DM) among Chinese young adults. Methods:.
Yan Chen +11 more
doaj +1 more source
A Mutation in the Insulin Receptor Substrate 2 Gene May Be Associated with Maturity-onset Diabetes of the Young: a Case Report with Genetic Analysis [PDF]
Zhongguo quanke yixue, 2023 Maturity-onset diabetes of the young (MODY) belongs to a kind of monogenic diabetes characterized by pancreatic β-cell dysfunction and high level of genetic heterogeneity.
REN Yumei, XU Min, YE Meilei, ZHANG Qiu, HU Honglin
doaj +1 more source
Journal of the Turkish Chemical Society, Section A: Chemistry, 2020 A simple, precise and accurate stability indicating isocratic Reverse Phase Ultra-Performance Liquid Chromatographic (RP-UPLC) method was developed for quantitative determination of Eltrombopag olamine in the presence of degradant products.
Ajay I PATEL +5 more
doaj +1 more source
Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment [PDF]
Yeungnam University Journal of Medicine, 2020 Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is
Kyung Mi Jang
doaj +1 more source