Results 1 to 10 of about 12,509 (161)

Targeted Sequencing Identifies Novel Variants in Common and Rare MODY Genes

Molecular Genetics & Genomic Medicine, 2019
Background Maturity‐onset diabetes of the young (MODY) is a form of monogenic diabetes with autosomal dominant inheritance. To date, mutations in 11 genes have been frequently associated with this phenotype.
Milena G Teles, Lílian A Caetano, Aline Dantas Costa-Riquetto   +2 more
exaly   +2 more sources

Genomic landscape of Mexican patients with maturity onset diabetes of the young: beyond mutations in MODY-known genes [PDF]

Frontiers in Endocrinology
IntroductionMaturity Onset Diabetes of the Young (MODY) remains an underdiagnosed condition with remarkable genetic variability across populations. While diagnostic tools are based on Caucasian cohorts, Whole Exome Sequencing (WES) studies are needed to ...
Alberto Moscona-Nissan, Daniel Marrero-Rodríguez, Sergio Andonegui-Elguera, Eduardo Salif Luna-Ávila, Florencia Martínez-Mendoza, Sandra Vela-Patiño, Itzel Ramírez-Ramos, Silvia Hinojosa-Alvarez, Jesus Hernandez-Perez, Rocio A. Chavez-Santoscoy, Sophia Mercado-Medrez, Kapy S. León-Wu, Regina De Miguel-Ibáñez, Moisés Mercado, Keiko Taniguchi-Ponciano, Aldo Ferreira-Hermosillo   +15 more
doaj   +2 more sources

Lipid profile indices in young people with GCK-MODY and HNF1A-MODY

Атеросклероз, 2022
Despite the fact that most young patients with hyperglycemia are diagnosed with type 1 (T1DM) and type 2 (T2DM) diabetes, up to 10 % of all cases of the disease are MODY diabetes.
Alla K. Ovsyannikova, Irina A. Belyaeva, Regina B. Galenok, Oksana D. Rymar   +3 more
doaj   +1 more source

When do we need to suspect maturity onset diabetes of the young in patients with type 2 diabetes mellitus?

Archives of Endocrinology and Metabolism, 2022
Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM).
Özlem Üstay, Tugçe Apaydın, Onur Elbasan, Hamza Polat, Gizem Günhan, Ceyda Dinçer, Lamia Şeker, Esra Arslan Ateş, Ayşegül Yabacı, Ahmet lter Güney, Dilek Gogas Yavuz   +10 more
doaj   +1 more source

Precision diabetes: Lessons learned from maturity‐onset diabetes of the young (MODY)

Journal of Diabetes Investigation, 2022
Maturity‐onset of diabetes of the young (MODY) are monogenic forms of diabetes characterized by early onset diabetes with autosomal dominant inheritance.
Mustafa Tosur, Louis H Philipson
doaj   +1 more source

Prevalence of maturity-onset diabetes of the young in phenotypic type 2 diabetes in young adults: a nationwide, multi-center, cross-sectional survey in China

Chinese Medical Journal, 2023
. Background:. Maturity-onset diabetes of the young (MODY) is the most common monogenic diabetes. The aim of this study was to assess the prevalence of MODY in phenotypic type 2 diabetes (T2DM) among Chinese young adults. Methods:.
Yan Chen, Jing Zhao, Xia Li, Zhiguo Xie, Gan Huang, Xiang Yan, Houde Zhou, Li Zheng, Tao Xu, Kaixin Zhou, Zhiguang Zhou, Lishao Guo   +11 more
doaj   +1 more source

Stability indicating analytical method development and validation of eltrombopag olamine in tablet dosage form by RP-UPLC

Journal of the Turkish Chemical Society, Section A: Chemistry, 2020
A simple, precise and accurate stability indicating isocratic Reverse Phase Ultra-Performance Liquid Chromatographic (RP-UPLC) method was developed for quantitative determination of Eltrombopag olamine in the presence of degradant products.
Ajay I PATEL, Shweta GOSAI, Kajal JADAV, Amit J. VYAS, Ashok B PATEL, Nilesh K PATEL   +5 more
doaj   +1 more source

MODI

Moderne mobilitet og infrastruktur, 2023
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Ragnhild Wahl, Lone-Eirin Lervåg
openaire   +1 more source

Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment [PDF]

Yeungnam University Journal of Medicine, 2020
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is
Kyung Mi Jang
doaj   +1 more source

A Mutation in the Insulin Receptor Substrate 2 Gene May Be Associated with Maturity-onset Diabetes of the Young: a Case Report with Genetic Analysis [PDF]

Zhongguo quanke yixue, 2023
Maturity-onset diabetes of the young (MODY) belongs to a kind of monogenic diabetes characterized by pancreatic β-cell dysfunction and high level of genetic heterogeneity.
REN Yumei, XU Min, YE Meilei, ZHANG Qiu, HU Honglin
doaj   +1 more source