Results 41 to 50 of about 23,962 (219)

Unkept Promises, Unequal Worlds: A Sociological Study of Intimate Abuse in Promise‐to‐Marry Cases in India

The British Journal of Sociology, EarlyView.
ABSTRACT The article presents a sociological study of promise‐to‐marry ‘rape’ cases in India to illuminate the inner lives of intimacies. It argues that promise‐to‐marry cases cannot be understood merely as instances of deceptive sex, wherein the consent of the victim is vitiated by a false promise of marriage as a pretext for sexual intercourse ...
Monika
wiley   +1 more source

Geneticheskie narusheniya pri sakharnom diabete vzroslogo tipa u molodykh (MODY)

Сахарный диабет, 2000
В большинстве случаев СД 2 типа определяется полигенными нарушениями, однако к настоящему времени известно несколько моногенных форм этого заболевания; среди последних наиболее изучен MODY. К настоящему времени различают 5 его форм, связанных с мутациями
Yu A Seregin, Timofey Alexandrovich Chistyakov, Aleksey Vadimovich Zilov, Valery Vyacheslavovich Nosikov, Ivan Ivanovich Dedov   +4 more
doaj   +1 more source

Study of homogenization on media milling time in preparation of irbesartan nanosuspension and optimization using design of experiments (DoE)

Future Journal of Pharmaceutical Sciences, 2020
Background The present investigation aimed at preparing nanosuspension of irbesartan to improve its dissolution. Dissolution enhancement of irbesartan can improve the oral bioavailability.
Chetan Borkhataria, Dhavalkumar Patel, Swati Bhagora, Nilesh Patel, Kalpesh Patel, Ravi Manek   +5 more
doaj   +1 more source

Clinical and genetic features of maturity-onset diabetes of the young in pediatric patients: a 12-year monocentric experience

Diabetology & Metabolic Syndrome, 2021
Background A retrospective observational study was conducted to assess the prevalence of maturity onset diabetes of the young (MODY) in a large paediatric population of Southern Italy newly diagnosed with diabetes.
Stefano Passanisi, Giuseppina Salzano, Bruno Bombaci, Fortunato Lombardo   +3 more
doaj   +1 more source

The DePICtion study: Implementing a diabetes classification tool in UK primary care—A qualitative study with primary care staff and patients

Diabetic Medicine, EarlyView.
Abstract Background The correct classification of diabetes (type 1, type 2 or rarer genetic forms) is essential for optimal treatment, but misclassification is common. The Diabetes in Primary Care Improving Classification (DePICtion) tool uses routinely collected clinical data to flag patients at risk of misclassification and prioritise them for ...
Charlotte Lee, Maddy Geen, Clare Timblin, Anita Hill, Katherine Young, Robin Humphreys, Angus Jones, Maggie Shepherd, Andrew T. Hattersley, Nadeem Qureshi, Beverley M. Shields, Katrina Turner   +11 more
wiley   +1 more source

Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus

JCRPE
INTRODUCTION: Maturity-onset diabetes of the young (MODY) is the most common type of monogenic diabetes. To date, mutations have been identified in 14 different genes of patients with a clinical diagnosis of MODY. This study screened mutations in 14 MODY-
Enver Şimşek, Oğuz Çilingir, Tülay Şimşek, Sinem Kocagil, Ebru Erzurumluoğlu Gökalp, Meliha Demiral, Çiğdem Binay   +6 more
doaj   +1 more source

Molecular genetics of maturity-onset diabetes of the young [PDF]

Терапевтический архив, 2016
To verify the type of diabetes mellitus (DM) remains an extremely important problem in endocrinology, as along with types 1 and 2 DM there are rarer hereditary types of DM, including maturity-onset diabetes of the young (MODY).
M I Voevoda, A A Ivanova, E V Shakhtshneider, A K Ovsyannikova, S V Mikhailova, K S Astrakova, S M Voevoda, O D Rymar   +7 more
doaj  

National clinical audits as distributed diabetes surveillance infrastructure: Consensus lessons from Ireland

Diabetic Medicine, EarlyView.
Ireland's national clinical audits capture valuable but fragmented diabetes‐related intelligence across paediatric diabetes, cardiovascular disease, critical care, stroke, hip fracture and hospital mortality. Abstract Background Diabetes increasingly shapes acute‐care demand through cardiovascular disease, critical illness, frailty, stroke and ...
Seif El Hadidi, Sean F. Dinneen, Gintare Valentelyte, Lauren Churchill, Nuala P. Murphy, Karina Hamilton, Edward W. Gregg   +6 more
wiley   +1 more source

Clinical characteristics, treatment, and treatment switch after molecular‐genetic classification in individuals with maturity‐onset diabetes of the young: Insights from the multicenter real‐world DPV registry

Journal of Diabetes
Background Individuals with maturity‐onset diabetes of the young (MODY) are often misdiagnosed as type 1 or type 2 diabetes and receive inappropriate care. We aimed to investigate the characteristics and treatment of all MODY types in a multicenter, real‐
Stefanie Lanzinger, Katharina Laubner, Katharina Warncke, Julia K. Mader, Sebastian Kummer, Claudia Boettcher, Torben Biester, Angela Galler, Daniela Klose, Reinhard W. Holl   +9 more
doaj   +1 more source

Genetics‐Informed Pharmacological Intervention in Gestational Diabetes Mellitus: Current Therapeutic Alignment, Emerging Targets and a Translational Roadmap

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Gestational diabetes mellitus (GDM) complicates roughly one in seven pregnancies and predicts later maternal type 2 diabetes mellitus (T2DM). Yet its pharmacological management still rests on a handful of agents (insulin, metformin and glibenclamide), none of them selected on the basis of the disease's molecular genetics.
Wael Osman
wiley   +1 more source