Results 51 to 60 of about 23,962 (219)
Hypoglycemic response to dorzagliatin in a patient with GCK-MODY
OBJECTIVEMetformin, insulin, and insulin secretagogues do not alter HbA1c levels in glucokinase-maturity-onset diabetes of the young (GCK-MODY). However, the efficacy of the new hypoglycemic drugs on GCK-MODY remains unclear.RESEARCH DESIGN AND METHODSWe
Tianhao Ba (14802617) +5 more
core +1 more source
, 2010 Maturity-onset diabetes of the young (MODY) is a heterogenous form of diabetes characterized by the early onset of diabetes, autosomal dominant inheritance, and impaired insulin secretion.
황, 진순
core +1 more source
GCK-MODY (MODY 2) Caused by a Novel p.Phe330Ser Mutation
ISRN Pediatrics, 2011 Maturity onset diabetes of the young (MODY) is a monogenic form of diabetes inherited as an autosomal dominant trait. The second most common cause is GCK-MODY due to heterozygous mutations in theGCKgene which impair the glucokinase function through different mechanisms such as enzymatic activity, protein stability, and increased interaction with its ...
Bonfig, Walter +7 more
openaire +2 more sources
Glycaemic Management and Pregnancy Outcomes in HNF1A‐MODY
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Introduction Birthweight of HNF1A‐affected offspring is largely similar to the background population with rarely reported cases of large for gestational age (LGA) and neonatal hypoglycaemia (NH). Conventional clinical management of pre‐gestational diabetes appears to be sufficient in managing HNF1A‐affected women in pregnancy.
M. T. Crowley +10 more
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background Among several approaches, k‐means clustering has established as a widely used method to classify people with type 2 diabetes (T2D) into distinct subphenotypes, and the Ahlqvist T2D subphenotypes of Severe Insulin Deficient Diabetes (SIDD), Mild Age‐Related Diabetes (MARD), Mild Obesity Diabetes (MOD) and Severe Insulin Resistant ...
Wolfgang Landgraf +3 more
wiley +1 more source
European Management Review, EarlyView.ABSTRACT Multi‐sided platform (MSP) models have become more relevant for incumbent companies, requiring them to develop MSP engagement strategies. This study sheds light on the complex process incumbents undergo in developing platform strategies. Adopting an inductive research design, we conducted interviews with 37 decision‐makers across 35 incumbent ...
Lukas Zechel, Vivek K. Velamuri
wiley +1 more source
Recognition of maturity‐onset diabetes of the young in China
Journal of Diabetes Investigation, 2021 Aims/Introduction Given that mutations related to maturity‐onset diabetes of the young (MODY) are rarely found in Chinese populations, we aim to characterize the mutation spectrum of MODY pedigrees.
Hua Liang +11 more
doaj +1 more source
Should Not Be Included in Diagnostic Testing for MODY
, 2022 Maturity-onset diabetes of the young (MODY) is an autosomal dominant form of monogenic diabetes, reported to be caused by variants in 16 genes. Concern has been raised about whether variants in BLK (MODY11), KLF11 (MODY7), and PAX4 (MODY9) cause MODY. We
Michael N. Weedon +26 more
core +1 more source
Political Accountability During Crises: Evidence From 40 Years of Financial Policies
International Economic Review, EarlyView.ABSTRACT We show that politicians facing a binding term limit are more likely to engage in financial deliberalization than those facing reelection, but only in the wake of a financial crisis. In particular, they implement policies that tend to favor incumbent financial institutions over the general population, such as increasing barriers to entry in ...
Orkun Saka, Yuemei Ji, Clement Minaudier
wiley +1 more source
Diabetes mellitus – analyser av genvarianter assosiert med subtyper av Maturity-Onset Diabetes of the Young (MODY) [PDF]
, 2022 Bakgrunn: MODY (Maturity-Onset Diabetes of the Young) er en arvelig form for ikkeinsulinavhengig type diabetes mellitus, forårsaket av sykdomsgivende genvariant i ett av mange MODY-gen.
Aukrust, Ingvild +1 more
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