Results 61 to 70 of about 23,263 (212)

GCK-MODY (MODY 2) Caused by a Novel p.Phe330Ser Mutation

ISRN Pediatrics, 2011
Maturity onset diabetes of the young (MODY) is a monogenic form of diabetes inherited as an autosomal dominant trait. The second most common cause is GCK-MODY due to heterozygous mutations in theGCKgene which impair the glucokinase function through different mechanisms such as enzymatic activity, protein stability, and increased interaction with its ...
Bonfig, Walter, Hermanns, Sandra, Warncke, Katharina, Eder, Gabriele, Engelsberger, Ilse, Burdach, Stefan, Ziegler, Annette Gabriele, Lohse, Peter   +7 more
openaire   +2 more sources

Political Accountability During Crises: Evidence From 40 Years of Financial Policies

International Economic Review, EarlyView.
ABSTRACT We show that politicians facing a binding term limit are more likely to engage in financial deliberalization than those facing reelection, but only in the wake of a financial crisis. In particular, they implement policies that tend to favor incumbent financial institutions over the general population, such as increasing barriers to entry in ...
Orkun Saka, Yuemei Ji, Clement Minaudier
wiley   +1 more source

Genotype, Phenotype, and Clinical Characteristics of Maturity-Onset Diabetes of the Young (MODY): Predominance of GCK-MODY

Objective: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes characterised by early-onset diabetes and inherited in an autosomal dominant manner.
Zeynep Esener, \uc7amtosun, Emine, \uc7ift\ue7i, Nurdan, İsmail Dündar, Leman Kayaş, Do\u11fan, Mustafa, Akinci, Aysehan, Esener, Zeynep, Nurdan Çiftçi, Ayşehan Akıncı, Kaya\u15f, Leman, Tekedereli, \u130brahim, Emine Çamtosun, Ciftci, Nurdan, Kayas, Leman, Ak\u131nc\u131, Ay\u15fehan, İbrahim Tekedereli, Dundar, Ismail, Tekedereli, Ibrahim, Camtosun, Emine, D\ufcndar, \u130smail, Mustafa Doğan   +21 more
core   +1 more source

Genetic testing for glucokinase mutations in clinically selected patients with MODY: a worthwhile investment [PDF]

, 2005
The differential diagnosis for children with diabetes includes a group of monogenic diabetic disorders known as maturity-onset diabetes of the young (MODY). So far, six underlying gene defects have been identified.
Schnyder, Sabine, Flück, Christa E., Hattersley, Andrew T., Mullis, Primus E., Ellard, Sian   +4 more
core   +1 more source

Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su, Yao Wei, Cheng Liu, Yafei Gao, Xiaolong Ma, Yongxin Li, Rui Qiao   +6 more
wiley   +1 more source

GLP-1 RA and dual GIP/GLP-1 RA treatment in MODY: a descriptive case series

BMJ Open Diabetes Research & Care
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and dual glucose insulinotropic polypeptide (GIP)/GLP-1 RA are widely prescribed, but their effectiveness in different subtypes of maturity-onset diabetes of the young (MODY) is unknown ...
William H Herman, Elif A Oral, Rochelle N Naylor, Brigid Gregg, Alina Z Mehdi, Lily Deng, Colby L Chase, Maria Cristina Foss-Freitas, Mansa Krishnamurthy, David T Broome   +9 more
doaj   +1 more source

Monogenic diabetes associated with PAX4 gene mutations (MODY9): first description in Russia

Сахарный диабет, 2017
Maturity-onset diabetes of the young (MODY) is a heterogeneous group of disorders characterised by autosomal dominant type of inheritance and caused by genetic defects leading to dysfunction of pancreatic beta-cells. To date, at least 13 subtypes of MODY
Natalya A. Zubkova, Olesya A. Gioeva, Vasiliy M. Petrov, Evgeny V. Vasiliev, Alexei V. Timofeev, Anna V. Abrukova, Anatoly N. Tiulpakov   +6 more
doaj   +1 more source

Cognitive reappraisal modulates neural responses to aversive sensory stimulation in autistic youth

Journal of Child Psychology and Psychiatry, EarlyView.
Background Sensory over‐responsivity (SOR) is highly prevalent and impairing in autism spectrum disorder (ASD). SOR has been associated with sensory‐limbic hyperresponsivity and reduced prefrontal top‐down regulation during sensory stimulation. There are few evidence‐based treatments for SOR, but cognitive reappraisal, an emotion regulation strategy ...
Urvi T. Shah, Karrin Evans, Megan Banchik, Apurva Chaturvedi, Sapna Ramappa, Katie Wong, Jennifer A. Silvers, Shulamite A. Green   +7 more
wiley   +1 more source

Genetic basis of Asian diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity‐onset diabetes of the young (MODY) and mitochondrial diabetes, highlights the importance of genetic diagnosis for subtype‐specific care.
Takafumi Ojima, Toshimasa Yamauchi
wiley   +1 more source

Mody C. Boatright (interview)

, 1969
This interview is included in the American Folklore Society Oral History Project held at the Archive of Folk Culture, American Folklife Center, Library of Congress, Washington, D.C. This oral history interview with folklorist Mody C.
Boatright, Mody Coggin, 1896-1970;
core