Results 1 to 10 of about 185,337,068 (295)

Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features

Case Reports in Endocrinology, 2021
Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy ...
Adnan Haider, Oksana Symczyk, Ayesha Hassan, Muhammad Atif Khan, Inderpreet Madahar, Dylan Holland   +5 more
doaj   +2 more sources

Molecular and clinical assessment of maturity-onset diabetes of the young revealed low mutational rate in Moroccan families

International Journal of Pediatrics & Adolescent Medicine, 2022
Background: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes characterized by autosomal dominant inheritance. To offer an adequate patient management and therapeutic treatment for MODY patients, in addition to an early ...
Said Trhanint, Laila Bouguenouch, Sana Abourazzak, Hanan El Ouahabi, Hanane Latrech, Salma Benyakhlef, Bahia Bennani, Ihssane El Bouchikhi, Fatima Zahra Moufid, Karim Ouldim, Lahsen El Ghadraoui, Nadia Maazouzi   +11 more
doaj   +1 more source

Prevalence of Obesity and Dyslipidemia in Maturity Onset Diabetes of the Young Patients

Endocrinology Research and Practice
Objective: Maturity-onset diabetes of the young (MODY) is an uncommon type of diabetes distinct from type 1 and type 2 diabetes. Diagnosis often depends on clinical suspicion, and misdiagnosis may lead to inappropriate treatment.
Murat Calapkulu, İlknur Öztürk Ünsal, Muhammed Erkam Sencar, Davut Sakiz, Mustafa Ozbek, Erman Cakal   +5 more
doaj   +1 more source

MODY: Strategies for a unique form of diabetes

Journal of Education and Health Promotion
Maturity-onset diabetes of the young (MODY) is a monogenic, autosomal dominant form of diabetes that typically presents before the age of 25. It is caused by mutations in single genes involved in insulin production and glucose regulation, leading to ...
Ram K. Garg
doaj   +1 more source

Update on clinical screening of maturity-onset diabetes of the young (MODY)

Diabetology & Metabolic Syndrome, 2020
Background Maturity-onset diabetes of the young (MODY) is the most common type of monogenic diabetes, being characterized by beta-cell disfunction, early onset, and autosomal dominant inheritance.
Renata Peixoto-Barbosa, André F. Reis, Fernando M. A. Giuffrida   +2 more
doaj   +1 more source

Identification and functional analysis of GCK gene mutations in 12 Chinese families with hyperglycemia

Journal of Diabetes Investigation, 2019
Aims/Introduction To investigate the clinical and genetic characteristics of Chinese patients with a phenotype consistent with maturity‐onset diabetes of the young type 2 and explore the pathogenic mechanism of their hyperglycemia.
Zhixin Wang, Chengming Diao, Yijing Liu, Mingmin Li, Jia Zheng, Qian Zhang, Miao Yu, Huabing Zhang, Fan Ping, Ming Li, Xinhua Xiao   +10 more
doaj   +1 more source

Molecular genetic analysis and clinical consideration of two families with GCK gene mutation [PDF]

Jichu yixue yu linchuang, 2020
Objective To explore the molecular genetics and clinical characteristics of two cases of maturity-onset diabetes of the young (MODY) type 2 caused by glucokinase (GCK) gene mutation.
WANG Zhi-xin, ZUO Qing-yao, LI Wei, CHEN Jia, DENG Wei
doaj  

Pathophysiology of diabetes: An overview

Avicenna Journal of Medicine, 2020
Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both ...
Mujeeb Z Banday, Aga S Sameer, Saniya Nissar   +2 more
doaj   +1 more source

Case Report: A Novel ABCC8 Variant in a Chinese Pedigree of Maturity-Onset Diabetes of the Young

Frontiers in Endocrinology, 2021
BackgroundWe aimed to analyze a novel ABCC8 variant of a Chinese patient with suspected maturity-onset diabetes of the young (MODY) and to provide evidence for precise diagnosis and appropriate treatment.MethodA Chinese family with suspected MODY was ...
Chaoyan Tang, Liheng Meng, Ping Zhang, Xinghuan Liang, Chaozhi Dang, Hui Liang, Junfeng Wu, Haiyun Lan, Yingfen Qin   +8 more
doaj   +1 more source

Treatment switch from multiple daily insulin injections to sulphonylureas in an African young adult diagnosed with HNF1A MODY: a case report

Journal of Medical Case Reports
Background Maturity onset diabetes of the young is one of the commonest causes of monogenic diabetes and can easily be mistaken for type 1 diabetes. A diagnosis of maturity onset diabetes of the young can have direct implications for genetic counseling ...
Jean Claude Katte, Mesmin Y. Dehayem, Kevin Colclough, Eugene Sobngwi   +3 more
doaj   +1 more source