Results 1 to 10 of about 11,891 (157)

A case of maturity‐onset diabetes of the young with a pathogenic HNF1A variant and a coexisting NEUROD1 variant [PDF]

Journal of Diabetes Investigation
Aims/Introduction Maturity‐onset diabetes of the young (MODY) accounts for at least 1%–5% of diabetes cases and is usually caused by single gene variants.
Tomofumi Takayoshi, Yushi Hirota, Kenji Sugawara, Aki Sugano, Mika Ohta, Takehito Takeuchi, Akane Yamamoto, Wataru Satake, Yutaka Takaoka, Wataru Ogawa   +9 more
doaj   +2 more sources

Recognition of maturity‐onset diabetes of the young in China [PDF]

Journal of Diabetes Investigation, 2021
Aims/Introduction Given that mutations related to maturity‐onset diabetes of the young (MODY) are rarely found in Chinese populations, we aim to characterize the mutation spectrum of MODY pedigrees.
Hua Liang, Yanan Zhang, Maixinyue Li, Jinhua Yan, Daizhi Yang, Sihui Luo, Xueying Zheng, Guoqing Yang, Zhuo Li, Wen Xu, Leif Groop, Jianping Weng   +11 more
doaj   +3 more sources

Maturity-Onset Diabetes of the Young (MODY): Genetic Causes, Clinical Characteristics, Considerations for Testing, and Treatment Options

Endocrines, 2021
Maturity Onset Diabetes of the Young (MODY) encompasses a group of rare monogenic forms of diabetes distinct in etiology and clinical presentation from the more common forms of Type 1 (autoimmune) and Type 2 diabetes.
Zoltan Antal
doaj   +3 more sources

Maturity‐onset diabetes of the young type 5 uncovered during pregnancy with a long‐term diagnosis of type 1 diabetes

Journal of Diabetes Investigation, 2019
We report a case of missed diagnosis of maturity‐onset diabetes of the young type 5 uncovered during pregnancy with a previous diagnosis of type 1 diabetes.
Mingqun Deng, Xiaojing Wang, Xinhua Xiao, Fan Ping   +3 more
doaj   +2 more sources

Molecular genetics of maturity-onset diabetes of the young [PDF]

Терапевтический архив, 2016
To verify the type of diabetes mellitus (DM) remains an extremely important problem in endocrinology, as along with types 1 and 2 DM there are rarer hereditary types of DM, including maturity-onset diabetes of the young (MODY).
M I Voevoda, A A Ivanova, E V Shakhtshneider, A K Ovsyannikova, S V Mikhailova, K S Astrakova, S M Voevoda, O D Rymar   +7 more
doaj   +3 more sources

Genetic Testing of Maturity-Onset Diabetes of the Young Current Status and Future Perspectives

Frontiers in Endocrinology, 2018
Diabetes is a global epidemic problem growing exponentially in Asian countries posing a serious threat. Among diabetes, maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic disorders that occurs due to β cell dysfunction ...
Parveena Firdous, Kamran Nissar, Sajad Ali, Bashir Ahmad Ganai, Uzma Shabir, Toyeeba Hassan, Shariq Rashid Masoodi   +6 more
doaj   +3 more sources

Clinical Manifestations and Biomarkers of the Maturity-Onset Diabetes of the Young

Endocrinology Research and Practice, 2023
Maturity-onset diabetes of the young is the most common monogenic diabetes form affecting between 1% and 5% of all diabetes cases. Clinical characteristics include young onset (usually before 45 years), autosomal dominant inheritance, absence of ...
İlhan Satman
doaj   +3 more sources

Maturity‐onset diabetes of the young (MODY) [PDF]

Diabetes/Metabolism Reviews, 1989
This review summarized aspects of the widening scope, phenotypic expression, natural history, recognition, pathogeneses, and heterogenous nature of maturity-onset diabetes of the young (MODY), an autosomal dominant inherited subtype of NIDDM, which can be recognized at a young age.
Fajan, S.S., Bell, G.I., Bowden, D.W., Halter, J.B., Polonsky, K.S.   +4 more
  +7 more sources

Maturity-onset diabetes of the young [PDF]

Life Sciences, 1994
Maturity-onset diabetes of the young (MODY) is a subtype of noninsulin dependent diabetes mellitus (NIDDM). It is characterized by an early age of onset and autosomal dominant mode of inheritance. These features and the availability of large multigenerational pedigrees make MODY useful for genetic studies of diabetes.
Fajans, Stefan S., Bell, Graeme I., Bowden, Donald W., Halter, Jeffrey B., Polonsky, Kenneth S.   +4 more
openaire   +5 more sources

Monogenic diabetes: recent updates on diagnosis and precision treatment: A narrative review [PDF]

Precision and Future Medicine, 2022
Monogenic diabetes is commonly caused by single-gene mutations. This disease ranges from 1% to 5% in all cases of diabetes and is less affected by behavior and environment.
Kyung Mi Jang
doaj   +1 more source