Results 21 to 30 of about 185,337,215 (295)

Hyperglycemia in pediatric age: could it be maturity onset diabetes of the young? Case reports and review of the literature [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Maturity Onset Diabetes of the Young (MODY) includes a clinically and genetically heterogeneous group of diabetes subtypes with MODY-2 being the second most prevalent form.
Mafalda Cascais, Ester Pereira, Alexandra Vieira, Margarida Venâncio, Lina Ramos, Pascoal Moleiro   +5 more
doaj   +1 more source

Maturity-onset diabetes of the young in children with incidental hyperglycemia: a multicenter Italian study of 172 families [PDF]

, 2009
OBJECTIVE - To investigate the prevalence of maturity-onset diabetes of the young (MODY) in Italian children With incidental hyperglycemia. RESEARCH DESIGN AND METHODS - Among 748 subjects age 1-18 years with incidental hyperglycemia, minimal diagnostic ...
ITALIAN SOCIETY OF PEDIATRIC ENDOCRINOLOGY AND DIABETOLOGY ISPED STUDY GROUP, Minuto, N, N. Minuto, C. Klersy, Lorini, R, O. Massa, Klersy, C, O. F. Pediatric Endocrinology Italian Society, d'Annunzio G, F. Cerutti, Manca Bitti, ML, S. Toni, FRANZESE, ADRIANA, Klersy C, G. D'Annunzio, Massa, O, Meschi, F, F. Barbetti, VANELLI, Maurizio, Meschi F, F. Meschi, Barbetti F, Italian Society of Pediatric Endocrinology, Italian Society of Pediatric Endocrinology and Diabetology (ISPED) Study Group, Iafusco D, Diabetology Study G.r.o.u.p., Minuto N, Bellannè Chantelot C, Iafusco, D, Frongia, A, Massa O, Cerutti F, Barbetti, F, Frongia AP, Toni S, Cerutti, F, Frongia, Ap, R. Lorini, C. Bellanne Chantelot, D. Iafusco, SULLI, Nicoletta, Lorini R, Toni, S, IAFUSCO, Dario, A. P. Frongia, Diabetology Study Group, Pinelli L., D'Amato E., Bellannè-Chantelot, C, Sulli N., Cotellessa M., Franzese A., Guazzarotti L., Lorini R., Pocecco M., Meschi F., Cadario F., Crino A., Toni S., Mancabitti M. L., Meossi C., Visentin A., Cappa M., Cherubini V., Vanelli M., Massa O., Frongia A. P., Bellanne-Chantelot C., Scaramuzza A., Banin P., Minuto N., Chiari G., Iafusco D., Klersy C., Barbetti F., d'Annunzio, G, Cerutti, Franco, Calisti L., Iughetti L., D'Annunzio G., Cerutti F., Cauvin V.   +81 more
core   +1 more source

Association of GCK Gene Promoter Polymorphism and their Role in its mRNA Expression among Type 2 Diabetes Mellitus Patients [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Glucokinase (GCK) gene alteration or inactivation leads to Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes. Alterations in GCK gene has been shown to be associated with increased risk of type 2 diabetes, hyperglycaemia
WASEEM FATIMA, Farah Khan, Ashraf Ali, Amit Kumar Verma   +3 more
doaj   +1 more source

Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment [PDF]

Yeungnam University Journal of Medicine, 2020
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is
Kyung Mi Jang
doaj   +1 more source

Identification of Maturity-Onset Diabetes of the Young Caused by Glucokinase Mutations Detected Using Whole-Exome Sequencing [PDF]

Endocrinology and Metabolism, 2017
Glucokinase maturity-onset diabetes of the young (GCK-MODY) represents a distinct subgroup of MODY that does not require hyperglycemia-lowering treatment and has very few diabetes-related complications. Three patients from two families who presented with
Eun-Hee Cho, Jae Woong Min, Sun Shim Choi, Hoon Sung Choi, Sang-Wook Kim   +4 more
doaj   +1 more source

Pregnancy outcome of Japanese patients with glucokinase–maturity‐onset diabetes of the young

Journal of Diabetes Investigation, 2019
Aims/Introduction Glucokinase–maturity‐onset diabetes of the young (GCK‐MODY; also known as MODY2) is a benign hyperglycemic condition, which generally does not require medical interventions.
Yuki Hosokawa, Shinji Higuchi, Rie Kawakita, Ikue Hata, Tatsuhiko Urakami, Tsuyoshi Isojima, Kei Takasawa, Yohei Matsubara, Haruo Mizuno, Yoshihiro Maruo, Katsuyuki Matsui, Katsuya Aizu, Kazuhiko Jinno, Shunsuke Araki, Yasuko Fujisawa, Koji Osugi, Chikako Tono, Yasuhiro Takeshima, Tohru Yorifuji   +18 more
doaj   +1 more source

Diabetic Lipemia with Maturity-Onset Diabetes of the Young.

Internal Medicine, 1997
A 19-year-old woman with diabetic lipemia and maturity-onset diabetes of the young (MODY) is reported. Though her insulin secretory activity was preserved, she fell into mild diabetic ketoacidosis (DKA) and showed type V hyperlipidemia. Post-heparin plasma activity of lipoprotein lipase (LPL) was decreased even 10 days after initiating insulin ...
KADOTA-SHINOZAKI, Aya, NAKAMURA, Taka-aki, HIDAKA, Hideki, KOJIMA, Hideto, YASUDA, Hitoshi, KASHIWAGI, Atsunori, KIKKAWA, Ryuichi   +6 more
openaire   +3 more sources

Dorzagliatin, a dual-acting glucokinase activator, increases insulin secretion and glucose sensitivity in glucokinase-maturity-onset diabetes of the young (GCK-MODY) and recent-onset type 2 diabetes

, 2022
Glucokinase-maturity-onset diabetes of the young (GCK-MODY) is caused by heterozygous inactivating mutations in glucokinase (GK, gene symbol GCK) and impaired glucose sensing.
Li Chen (5749), Ronald CW Ma (8985394), Cadmon KP Lim (8985365), Sandra TF Tsoi (14007694), Ele Ferrannini (248028), Juliana CN Chan (8712420), Andrea Mari (297970), Ke Wang (82395), Andrea OY Luk (14007697), Elaine Chow (8473992), Baoqi Fan (8985353), Emily Poon (3525038)   +11 more
core   +1 more source

Maturity-onset diabetes of the young and pregnancy

, 2023
Maturity-onset diabetes of the young (MODY) is a group of hereditary monogenetic forms of diabetes. MODY accounts for 1-3% of all persons with diabetes but is often undiagnosed or misdiagnosed as type 1 diabetes, type 2 diabetes, or gestational diabetes.
Thuesen, Anne Cathrine, Damm, Peter, Hansen, Torben, Kauffmann, Anna, Ringholm, Lene, Mathiesen, Elisabeth Reinhardt, Clausen, Tine Dalsgaard, Jørgensen, Isabella Lindegaard   +7 more
core   +1 more source

Genetic variants and characterization of MODY in a single, large pediatric referral center

Journal of Clinical & Translational Endocrinology
Background: Identifying Maturity-onset diabetes of the young (MODY) is essential as treatment differs from other forms of diabetes. Clinical characteristics and MODY probability calculator (MPC) scores were evaluated in patients with MODY.
Lily Deng, Amy S. Shah, Mansa Krishnamurthy   +2 more
doaj   +1 more source