Results 31 to 40 of about 11,891 (157)
Molecular genetic analysis and clinical consideration of two families with GCK gene mutation [PDF]
Jichu yixue yu linchuang, 2020 Objective To explore the molecular genetics and clinical characteristics of two cases of maturity-onset diabetes of the young (MODY) type 2 caused by glucokinase (GCK) gene mutation.
WANG Zhi-xin, ZUO Qing-yao, LI Wei, CHEN Jia, DENG Wei
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Pathophysiology of diabetes: An overview
Avicenna Journal of Medicine, 2020 Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both ...
Mujeeb Z Banday +2 more
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Journal of Diabetes Investigation, 2019 Aims/Introduction To investigate the clinical and genetic characteristics of Chinese patients with a phenotype consistent with maturity‐onset diabetes of the young type 2 and explore the pathogenic mechanism of their hyperglycemia.
Zhixin Wang +10 more
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Case Report: A Novel ABCC8 Variant in a Chinese Pedigree of Maturity-Onset Diabetes of the Young
Frontiers in Endocrinology, 2021 BackgroundWe aimed to analyze a novel ABCC8 variant of a Chinese patient with suspected maturity-onset diabetes of the young (MODY) and to provide evidence for precise diagnosis and appropriate treatment.MethodA Chinese family with suspected MODY was ...
Chaoyan Tang +8 more
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Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
Case Reports in Endocrinology, 2021 Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy ...
Adnan Haider +5 more
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[Mature onset diabetes of the young (MODY)].
Acta medica portuguesa, 2002 Maturity-onset diabetes of the young (MODY) is a rare form of juvenile diabetes mellitus, defined by early onset, absence of ketosis, non-insulin-dependent diabetes and autosomal dominant inheritance. Advances in molecular genetic analysis have identified mutations accounting for different MODY subtypes, all of them associated with defects of insulin ...
E Lacerda Nobre +4 more
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Investigating maturity onset diabetes of the young.
The Clinical biochemist. Reviews, 2009 Maturity Onset Diabetes of Young (MODY) is a monogenic and autosomal dominant form of diabetes mellitus with onset of the disease often before 25 years of age. It is due to dysfunction of pancreatic beta cells characterised by non-ketotic diabetes and absence of pancreatic auto-antibodies.
Nyunt, Ohn +7 more
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Journal of Medical Case ReportsBackground Maturity onset diabetes of the young is one of the commonest causes of monogenic diabetes and can easily be mistaken for type 1 diabetes. A diagnosis of maturity onset diabetes of the young can have direct implications for genetic counseling ...
Jean Claude Katte +3 more
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Journal of Diabetes Investigation, 2020 We present the case of a 12‐year‐old Japanese girl, who was positive for markers of both maturity‐onset diabetes of the young and latent autoimmune diabetes in youth.
Kei Yoshida +4 more
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Maturity-Onset Diabetes of the Young Identified Among Algerian Probands with Early-Onset Diabetes
Diabetes, Metabolic Syndrome and Obesity, 2020 Faiza Bouldjennet,1,* Anette P Gjesing,2,* Malha Azzouz,3 Samir Ait Abderrahman,4 Amina El Guecier,5 Said Ali,6 Brahim Oudjit,4 Farida Mennadi-Lacete,7 Lyèce Yargui,6 Aissa Boudiba,3 Ahcène Chibane,5 Chafia Touil-Boukoffa,1 Torben Hansen,2 ...
Bouldjennet F +13 more
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