Results 21 to 30 of about 185,337,068 (295)

Monogenic diabetes: recent updates on diagnosis and precision treatment: A narrative review [PDF]

Precision and Future Medicine, 2022
Monogenic diabetes is commonly caused by single-gene mutations. This disease ranges from 1% to 5% in all cases of diabetes and is less affected by behavior and environment.
Kyung Mi Jang
doaj   +1 more source

A case of maturity-onset diabetes of the young type 4 in Korea [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Maturity-onset diabetes of the young (MODY) is a rare, autosomal dominant disease characterized by non-ketogenic diabetes mellitus (DM). MODY type 4, caused by PDX1 mutation, is a very rare subtype of MODY, especially in Korea.
Geu-Meum Park, Soojung Lee, Ja Young Seo, Kyung In Lim   +3 more
doaj   +1 more source

Targeted gene panel analysis of Japanese patients with maturity‐onset diabetes of the young‐like diabetes mellitus: Roles of inactivating variants in the ABCC8 and insulin resistance genes

Journal of Diabetes Investigation, 2023
Aims/Introduction To investigate the genetic background of Japanese patients with suspected maturity‐onset diabetes of the young (MODY). Materials and Methods On 340 proband patients referred from across Japan, genomic variants were analyzed using a ...
Tohru Yorifuji, Yoh Watanabe, Kana Kitayama, Yuki Yamada, Shinji Higuchi, Jun Mori, Masaru Kato, Toru Takahashi, Tokuko Okuda, Takane Aoyama   +9 more
doaj   +1 more source

When do we need to suspect maturity onset diabetes of the young in patients with type 2 diabetes mellitus?

Archives of Endocrinology and Metabolism, 2022
Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM).
Özlem Üstay, Tugçe Apaydın, Onur Elbasan, Hamza Polat, Gizem Günhan, Ceyda Dinçer, Lamia Şeker, Esra Arslan Ateş, Ayşegül Yabacı, Ahmet lter Güney, Dilek Gogas Yavuz   +10 more
doaj   +1 more source

Maturity-Onset Diabetes of the Young (MODY): Genetic Causes, Clinical Characteristics, Considerations for Testing, and Treatment Options

Endocrines, 2021
Maturity Onset Diabetes of the Young (MODY) encompasses a group of rare monogenic forms of diabetes distinct in etiology and clinical presentation from the more common forms of Type 1 (autoimmune) and Type 2 diabetes.
Zoltan Antal
doaj   +1 more source

Testing for monogenic diabetes is lower than required to reveal its true prevalence in an Australian population

Diabetes Epidemiology and Management, 2022
Aims: Monogenic diabetes is responsible for 1–5% of all cases of diabetes. A previous Australian study estimated a prevalence of 89 cases per million adults, or one in 280 people with diabetes.
Aleena S. Ali, Jay C.S. Wong, Ainsley Campbell, Elif I. Ekinci   +3 more
doaj   +1 more source

Maturity-onset diabetes of the young: A proposal for updated nomenclature. [PDF]

J Diabetes Investig
Given the contemporary understanding of diabetes genetics, the term maturity-onset diabetes of the young (MODY) warrants renaming.
Tosur M.
europepmc   +2 more sources

Homozygous hypomorphic HNF1A alleles are a novel cause of young-onset diabetes and result in sulphonylurea sensitive diabetes [PDF]

, 2020
OBJECTIVE Heterozygous loss-of-function mutations in HNF1A cause maturity-onset diabetes of the young (MODY). Affected individuals can be treated with low-dose sulphonylureas.
Colclough, Kevin, hassanali, neelam, Misra, Shivani, Valabhji, Jonathan, Bennet, Amanda, Gloyn, Anna, Oliver, Nick, Juszczak, Agata, Ellard, Sian, Caswell, Richard   +9 more
core   +1 more source

Objective and Subjective Sleep Patterns in Adults with Maturity-Onset Diabetes of the Young (MODY)

, 2023
   Article highlights: a) To examine sleep patterns in patients with Maturity-Onset Diabetes of the Young. b) Are sleep disturbances common in Maturity-Onset Diabetes of the Young?
Louis H. Philipson (8561265), Maria V. Salguero (14280215), Kristen Wroblewski (614763), Esra Tasali (14280220), Rochelle N. Naylor (9140375), Marilyn Arosemena (14280206)   +5 more
core   +1 more source

Hyperglycemia in pediatric age: could it be maturity onset diabetes of the young? Case reports and review of the literature [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Maturity Onset Diabetes of the Young (MODY) includes a clinically and genetically heterogeneous group of diabetes subtypes with MODY-2 being the second most prevalent form.
Mafalda Cascais, Ester Pereira, Alexandra Vieira, Margarida Venâncio, Lina Ramos, Pascoal Moleiro   +5 more
doaj   +1 more source