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Hyperglycemia in pediatric age: could it be maturity onset diabetes of the young? Case reports and review of the literature [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Maturity Onset Diabetes of the Young (MODY) includes a clinically and genetically heterogeneous group of diabetes subtypes with MODY-2 being the second most prevalent form.
Mafalda Cascais, Ester Pereira, Alexandra Vieira, Margarida Venâncio, Lina Ramos, Pascoal Moleiro   +5 more
doaj   +1 more source

High prevalence of maturity onset diabetes of the young (MODY) among Indians [PDF]

, 1985
This article describes the high prevalence of maturity-onset diabetes in the young (MODY) in an Indian clinic population of diabetic patients. MODY appears to be more common among Indians than among Caucasians.
Viswanathan, Moopil, Mohan, Rema, Mohan, Viswanathan, Ramachandran, Ambady, Snehalatha, Chamukuttan, Bharani, Gopalan   +5 more
core   +2 more sources

Association of GCK Gene Promoter Polymorphism and their Role in its mRNA Expression among Type 2 Diabetes Mellitus Patients [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Glucokinase (GCK) gene alteration or inactivation leads to Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes. Alterations in GCK gene has been shown to be associated with increased risk of type 2 diabetes, hyperglycaemia
WASEEM FATIMA, Farah Khan, Ashraf Ali, Amit Kumar Verma   +3 more
doaj   +1 more source

Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment [PDF]

Yeungnam University Journal of Medicine, 2020
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is
Kyung Mi Jang
doaj   +1 more source

Identification of Maturity-Onset Diabetes of the Young Caused by Glucokinase Mutations Detected Using Whole-Exome Sequencing [PDF]

Endocrinology and Metabolism, 2017
Glucokinase maturity-onset diabetes of the young (GCK-MODY) represents a distinct subgroup of MODY that does not require hyperglycemia-lowering treatment and has very few diabetes-related complications. Three patients from two families who presented with
Eun-Hee Cho, Jae Woong Min, Sun Shim Choi, Hoon Sung Choi, Sang-Wook Kim   +4 more
doaj   +1 more source

Pregnancy outcome of Japanese patients with glucokinase–maturity‐onset diabetes of the young

Journal of Diabetes Investigation, 2019
Aims/Introduction Glucokinase–maturity‐onset diabetes of the young (GCK‐MODY; also known as MODY2) is a benign hyperglycemic condition, which generally does not require medical interventions.
Yuki Hosokawa, Shinji Higuchi, Rie Kawakita, Ikue Hata, Tatsuhiko Urakami, Tsuyoshi Isojima, Kei Takasawa, Yohei Matsubara, Haruo Mizuno, Yoshihiro Maruo, Katsuyuki Matsui, Katsuya Aizu, Kazuhiko Jinno, Shunsuke Araki, Yasuko Fujisawa, Koji Osugi, Chikako Tono, Yasuhiro Takeshima, Tohru Yorifuji   +18 more
doaj   +1 more source

Genotype, Phenotype, and Clinical Characteristics of Maturity-Onset Diabetes of the Young (MODY): Predominance of <i>GCK</i>-MODY [PDF]

J Clin Res Pediatr Endocrinol
Objective: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes characterised by early-onset diabetes and inherited in an autosomal dominant manner.
Kayaş L, Akıncı A, Çamtosun E, Dündar İ, Çiftçi N, Esener Z, Tekedereli İ, Doğan M.   +7 more
europepmc   +2 more sources

Diabetic Lipemia with Maturity-Onset Diabetes of the Young.

Internal Medicine, 1997
A 19-year-old woman with diabetic lipemia and maturity-onset diabetes of the young (MODY) is reported. Though her insulin secretory activity was preserved, she fell into mild diabetic ketoacidosis (DKA) and showed type V hyperlipidemia. Post-heparin plasma activity of lipoprotein lipase (LPL) was decreased even 10 days after initiating insulin ...
KADOTA-SHINOZAKI, Aya, NAKAMURA, Taka-aki, HIDAKA, Hideki, KOJIMA, Hideto, YASUDA, Hitoshi, KASHIWAGI, Atsunori, KIKKAWA, Ryuichi   +6 more
openaire   +3 more sources

'Join Us On Our Journey': developing a new model of care for children and young people with type 1 diabetes Final report for NHS Diabetes [PDF]

, 2012
The aims of this research were to develop a model of care that will deliver the aspirations of the policy document, ‘Making Every Young Person with Diabetes Matter’ and improve the care provision for children and young people with Type 1 diabetes in ...
Carlin, E, Kime, NH
core   +6 more sources

Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis [PDF]

, 2011
Monozygotic (MZ) twin pair discordance for childhood-onset Type 1 Diabetes (T1D) is similar to 50%, implicating roles for genetic and non-genetic factors in the aetiology of this complex autoimmune disease.
Busato, F, Manfras, B, Kerith-rae M, Leslie, R. David, Jörg Tost, Manfras Burkhard, Mohammed I Hawa, Thomas A. Down, Maslau, S, Leslie, RD, Mohammed I. Hawa, Bernhard O Boehm, Beck Stephan, Rakyan, VK, Aden Deeqo, Daunay, A, Maslau Siarhei, Down Thomas A., Dias, Kerith-Rae M., Bell, Christopher G., Rakyan, Vardhman K., Boehm, Bernhard O., Beck, S, Bell Christopher G., Leslie R. David, Charles A. Mein, Charles A Mein, Boehm Bernhard O., Vardhman K Rakyan, Beyan, H, Burkhard Manfras, Christopher G. Bell, Hawa, MI, Kerith-Rae M. Dias, Vardhman K. Rakyan, R David Leslie, Kerith-Rae M Dias, Siarhei Maslau, Hawa Mohammed I., Busato Florence, Deeqo Aden, Bell, CG, Beck, Stephan, Stephan Beck, Bernhard O. Boehm, Busato, Florence, Dias Kerith-Rae M., Tost Jörg, Mein, Charles A., Christopher G Bell, Dias, KRM, Tost, J, Maslau, Siarhei, Hawa, Mohammed I., Daunay, Antoine, R. David Leslie, Florence Busato, Down, Thomas A., Rakyan Vardhman K., Tost, Jörg, Mein, CA, Daunay Antoine, Beyan, Huriya, Down, TA, Boehm, BO, Huriya Beyan, Antoine Daunay, Mein Charles A., Manfras, Burkhard, Thomas A Down, Beyan Huriya, Aden, D, Aden, Deeqo   +72 more
core   +2 more sources