Results 121 to 130 of about 40,166 (303)

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

Bridging the gap in clinical research training: a qualitative study of postgraduate medical students' perceptions of good clinical practice education

Medical Education Online
Objectives Despite increasing emphasis on clinical research ethics and quality assurance, Good Clinical Practice (GCP) training remains inadequately incorporated into postgraduate medical education.
Wang Xiaoyun, Yin Zhao, Li Zeyun, Xi Chen, Jia Xuedong, Lai Yaowen, Wang Jie, Tian Xin   +7 more
doaj   +1 more source

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

The Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia, Veronica Mollica, Ondřej Fiala, Kazutoshi Fujita, Yüksel Ürün, Bohuslav Melichar, Javier Molina‐Cerrillo, Teresa Alonso‐Gordoa, Umberto Basso, Maria T. Bourlon, Emmanuel Seront, Ugo De Giorgi, Maria José Juan Fita, Pasquale Rescigno, Tarek Taha, Fernando C. Maluf, Alexandr Poprach, Simona De Summa, Tomas Buchler, Luca Galli, Jindrich Kopecky, Gaetano Aurilio, Jakub Kucharz, Carlo Messina, Gabriel Berlingieri Polho, Sarah Scagliarini, Francesco Grillone, Diogo Assed Bastos, Luigi Formisano, Gian Paolo Spinelli, Alessandra Mosca, Alessandro Rizzo, Aristotelis Bamias, Fernando Sabino Marques Monteiro, Andrey Soares, Francesco Massari, Andrew J. Armstrong, Matteo Santoni   +37 more
wiley   +1 more source

Regression of prostate cancer following administration of Genistein Combined Polysaccharide (GCP), a nutritional supplement: a case report.

, 2002
PURPOSE: It has been reported that genistein, an isoflavone used in soybeans, has antiprostate cancer effects. Genistein Combined Polysaccharide (GCP trade mark; AMino Up, Sapporo, Japan), a nutritional supplement manufactured in Japan, is composed of ...
Ghafar, Mohamed A, Bingham, Jonathan B, MD, Mansukhani, Mahesh M, Katz, Aaron E, Anastasiadis, Aristotelis Georgios, Golliday, Erica   +5 more
core   +1 more source

Automatic SAR/optical cross-matching for GCP monograph generation

, 2016
Ground Control Points (GCP), automatically extracted from Synthetic Aperture Radar (SAR) images through 3D stereo analysis, can be effectively exploited for an automatic orthorectification of optical imagery if they can be robustly located in the basic ...
La Mantia, C., Tupin, Sobel, Brant Howard, Morea, A., Agrimano, L., Chiaradia, MT., Nitti, Prewitt, Nitti, DO., Samarelli, S., Nutricato, R., Sjanic   +12 more
core   +1 more source

Practical Methodology for Developing Visions for Carbon‐Neutral Cities and Communities

Sustainable Development, EarlyView.
ABSTRACT Cities and communities play important roles in sustainable development and climate change mitigation. This study presents a novel framework for developing carbon‐neutral visions for cities and communities. We established five “principles,” investigated options encompassing four parameters (management, goal setting, actions, and quantification),
Kei Gomi, Makoto Ooba, Shogo Nakamura, Kohei Sakai, Satoshi Nagatomi   +4 more
wiley   +1 more source

Exploration of High and Low Frequency Options for Subperception Spinal Cord Stimulation Using Neural Dosing Parameter Relationships: The HALO Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Subperception spinal cord stimulation (SCS) is described mostly utilizing waveforms that require high energy. However, the necessity of these waveforms for effective subperception has not been established. We aimed to explore whether effective subperception pain relief can be achieved using frequencies below 1 kHz.
José Paz‐Solís, Simon Thomson, Roshini Jain, Lilly Chen, Ismael Huertas, Que Doan   +5 more
wiley   +1 more source

An Islamic Perspective on the Sustainable Development Goals: Exploring Key Challenges From the Ravi Riverfront Urban Development Project

Sustainable Development, EarlyView.
ABSTRACT Projects are typically viewed as mechanisms for delivering products and services; however, this study examines projects from the distinct perspective of grand challenges (GCs). The selected case is the Ravi Riverfront Urban Development Project in Lahore, Pakistan—a grand challenge project (GCP).
Rehab Iftikhar, Syed Nayyer Abbas Kazmi
wiley   +1 more source

Programmed Cell Death in Diabetic Kidney Disease: Mechanisms and Therapeutic Targeting

Journal of Inflammation Research
Shanshan Tang,1,* Yuting Sun,2,* Wenjie Sun,3,4,* Xiaomin Kang,2 Xuefei Zhao,2 Linlin Jiang,2 Qing Gao,2 Xuedong An,2 Hangyu Ji,2 Fengmei Lian2 1College of Traditional Chinese Medicine, Changchun University of Chinese Medicine ...
Tang S, Sun Y, Sun W, Kang X, Zhao X, Jiang L, Gao Q, An X, Ji H, Lian F   +9 more
doaj  

The role of beta-glucuronidase in induction of apoptosis by genistein combined polysaccharide (GCP) in xenogeneic mice bearing human mammary cancer cells

, 2003
In order to reveal the mechanisms underlying genistein combined polysaccharide (GCP) inhibition of tumor proliferation, we investigated the effects of GCP on the growth of human breast cancer cells transplanted to athymic nude mice.
CHIHIRO WAGATSUMA, YOUNG‐JOON SURH, LAN YUAN, Wagatsuma, Chihiro, Sun, BuXiang, BUXIANG SUN, Kim, Jung‐Hwan, Surh, Young‐Joon, Yuan, Lan, JUNG‐HWAN KIM   +9 more
core   +1 more source