Results 141 to 150 of about 40,166 (303)

Research Staff's Experiences of Applying the UNCRC in Clinical Research Involving Young Children—An Ongoing Process of Ethical Judgement

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim An estimated five million children under the age of five die each year, largely from preventable causes. Clinical research involving young children is essential for improving child health, but is ethically complex. The United Nations Convention on the Rights of the Child (UNCRC) provides a framework for protecting children's rights and ...
Anna Karin Bernhardsson, Anna Gustafsson
wiley   +1 more source

The TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche   +9 more
wiley   +1 more source

GCP [PDF]

open access: yes, 2019
openaire   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

open access: yesBioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins   +2 more
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

open access: yesBJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui   +2 more
wiley   +1 more source

High‐Gloss SVBRDF Capture Using Bounce Light

open access: yesComputer Graphics Forum, EarlyView.
Abstract Reflectance capture aims at the visual reproduction of an object under varying illumination. Past works differ substantially in their experimental overhead, from single‐ or few‐image approaches, that employ significant (often learned) priors at the expense of biased reconstructions, to more accurate approaches that tend to be time‐consuming ...
Tomáš Iser   +2 more
wiley   +1 more source

Methods of GCP ability training for residents

open access: yesAsian Journal of Surgery, 2023
Guang-Min Xu   +3 more
openaire   +3 more sources

Contouring Signed Distance Fields by Approximating Gradients

open access: yesComputer Graphics Forum, EarlyView.
Abstract Signed distance fields are often represented by discrete samples (e.g., on a grid). Recovering the contour implicitly represented by the distance samples requires an approximation algorithm. Several recent approaches have shown that exploiting the information carried in each distance sample by explicitly constructing a surface point gives ...
M. Kohlbrenner, M. Alexa
wiley   +1 more source

‘They Are So Tall They Almost Reach the Sun’: Children's Experiences, Perceptions and Agency in Early Childhood School Spaces Through Participatory Research

open access: yesChildren &Society, EarlyView.
ABSTRACT This article studies how children between the ages of three and five perceive, inhabit, and assign meaning to school environments through a collaborative qualitative research design that emphasises children's agency and diverse forms of expression.
Katia Álvarez Díaz   +2 more
wiley   +1 more source

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