Preparation of Gemini-Functionalized Cellulose Paper Sorptive Phases for Enrichment of Non-Steroidal Anti-Inflammatory Drugs in Water. [PDF]
Luo S +5 more
europepmc +1 more source
ABSTRACT Aim This Phase 1 program evaluated the safety, tolerability, pharmacokinetics and exploratory pharmacodynamics of the novel melanin‐concentrating hormone receptor‐1 antagonist RGH‐706. Methods Study A was a first‐in‐man, randomized trial comprising a double‐blind, placebo‐controlled single‐ascending‐dose part (0.1–162.5 mg) and a two‐way ...
Thomas Brevig +10 more
wiley +1 more source
Comparative Evaluation of 16S rRNA Target Regions Using PCR High-Resolution Melt Curve Analysis for Differentiation of Bacteria Associated with Bovine Mastitis. [PDF]
Jember TF +3 more
europepmc +1 more source
ABSTRACT Background Modern higher education requires a redefinition of pedagogical objectives to meet the evolving cognitive and perceptual demands of contemporary students. One such emerging objective is the cultivation of visual perceptions. Generational differences suggest that current students possess distinct cognitive profiles and learning ...
Adrienne Fazekas +7 more
wiley +1 more source
Uncovering smooth structures in single-cell data with neighbor embeddings guided by predictability-computability-stability. [PDF]
Ma R, Li X, Hu J, Yu B.
europepmc +1 more source
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Protease-Triggered Chromogenic Release From Peptide-Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity. [PDF]
Hiruta Y +9 more
europepmc +1 more source
Yue-E Chen,1,* Guo-Lian Zhao,2,* Fei-Hu Liu1 1GCP Institution Office, Xi’an Chest Hospital, Chest Hospital Affiliated to Northwest University, Xi’an, 710100, People’s Republic of China; 2Department of Clinical Laboratory, Xi’an Chest ...
Chen YE, Zhao GL, Liu FH
doaj
Does increased awareness necessarily translate into investigator identity? [PDF]
Maynard O.
europepmc +1 more source
Targeted keratin repair: A plant‐based approach to hair strength and surface restoration
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge +6 more
wiley +1 more source

