Results 11 to 20 of about 29,893 (266)

PENGARUH JUMLAH DAN SEBARAN GCP PADA PROSES REKTIFIKASI CITRA WORLDVIEW II (Studi Kasus : Kota Kediri, Jawa Timur)

open access: yesGeoid, 2015
Pada penelitian ini dilakukan uji coba penggunaan titik kontrol tanah (GCP) secara variatif, yang terbagi menjadi 5 model jumlah dan distribusi titik kontrol tanah yaitu model 1 dan model 2 menggunakan jumlah 4 GCP dengan pola distribusi pada model 1 ...
Akbar Kurniawan   +2 more
doaj   +1 more source

The need for ‘Good Clinical Practice’ in health care research

open access: yesSouth African Family Practice, 2009
Randomised controlled trials form the foundation for ‘evidence-based-medicine’, but the results of such research can be relied upon only if it was conducted according to principles and standards collectively referred to as ‘Good Clinical Practice’ (GCP).
M.H.R. NoorZurani   +6 more
doaj   +1 more source

UV resonance Raman spectroscopy of the supramolecular ligand guanidiniocarbonyl indole (GCI) with 244 nm laser excitation

open access: yesBeilstein Journal of Organic Chemistry, 2020
Ultraviolet resonance Raman (UVRR) spectroscopy is a powerful vibrational spectroscopic technique for the label-free monitoring of molecular recognition of peptides or proteins with supramolecular ligands such as guanidiniocarbonyl pyrroles (GCPs).
Tim Holtum   +4 more
doaj   +1 more source

Disease modification and symptom relief in osteoarthritis using a mutated GCP‐2/CXCL6 chemokine

open access: yesEMBO Molecular Medicine, 2022
We showed that the chemokine receptor C‐X‐C Motif Chemokine Receptor 2 (CXCR2) is essential for cartilage homeostasis. Here, we reveal that the CXCR2 ligand granulocyte chemotactic protein 2 (GCP‐2) was expressed, during embryonic development, within the
Sara Caxaria   +23 more
doaj   +1 more source

A dose-escalation study of HP501, a highly selective URAT1 inhibitor, in male Chinese patients with hyperuricemia

open access: yesScientific Reports, 2023
HP501 is a highly selective renal urate transporter 1 (URAT1) inhibitor used for treating hyperuricemia. This study aimed to evaluate the tolerability, pharmacokinetics, and pharmacodynamics of HP501 in male Chinese patients.
Ruilin Ding   +13 more
doaj   +1 more source

The C-terminal domain of the novel essential protein Gcp is critical for interaction with another essential protein YeaZ of Staphylococcus aureus. [PDF]

open access: yesPLoS ONE, 2011
Previous studies have demonstrated that the novel protein Gcp is essential for the viability of various bacterial species including Staphylococcus aureus; however, the reason why it is required for bacterial growth remains unclear.
Ting Lei   +6 more
doaj   +1 more source

Assessing clinical research coordinator knowledge of good clinical practice: An evaluation of the state of the art and a test validation study

open access: yesJournal of Clinical and Translational Science, 2020
This paper describes the development and validation of a new 32-item test of knowledge of good clinical practice (GCP) administered to 625 clinical research coordinators.
James M. DuBois   +4 more
doaj   +1 more source

Drug Import Replacement Is a Perspective Direction of the Development of Russian Economy

open access: yesУправленческое консультирование, 2018
The development of the domestic pharmaceutical industry as a science-intensive and hightech sector of the country’s economy is, among other things, a pledge of the drug safety of the state, especially in the conditions of a modern complex political ...
K. D. Grigorieva
doaj   +1 more source

The essentiality of staphylococcal Gcp is independent of its repression of branched-chain amino acids biosynthesis. [PDF]

open access: yesPLoS ONE, 2012
Our previous studies revealed that the staphylococcal protein Gcp is essential for bacterial growth; however, the essential function of Gcp remains undefined.
Ting Lei   +5 more
doaj   +1 more source

Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells

open access: yesFrontiers in Pharmacology, 2021
Glucocappasalin (GCP), a natural product derived from the seeds of Descurainia sophia (L.) Webb. ex Prantl, exhibits potential antitumor activity in HeLa cervical carcinoma cells.
Guangya Xu   +9 more
doaj   +1 more source

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