Results 21 to 30 of about 29,893 (266)

Evaluation of Ornidazole Tablets Bioequivalence in Chinese Healthy Participants Under Fasted and Fed Conditions Using Pharmacokinetic Parameters

Drugs in R&D
Background and Objective Ornidazole, the third generation of nitroimidazole derivatives after metronidazole and tinidazole, it exerts both bactericidal and antiprotozoal effects.
Yanrong Wang, Yuanyuan He, Weihong Li, Hongmin LI, Liyuan Tang, Xinya Dai, Yingzi Pei, Lijing Gao   +7 more
doaj   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Clusterization‐Triggered Emission from Cellulose‐Based Luminophores in Dilute Aqueous Solution through Imine Formation

Advanced Functional Materials, EarlyView.
Clusterization‐triggered emission is realized in dilute aqueous solution by introducing imine linkages into cellulose‐based luminophores. Imine functionalization creates O/N‐rich, hydrogen‐bonded clustered microenvironments that stabilize emissive states and restrict molecular motions. Luminescence is tunable by amine type and multiplicity.
Yazhou Su, Akihide Sugawara, Madhurangika Panchabashini Horathal Pedige, Youhei Takeda, Satoshi Minakata, Hiroshi Uyama   +5 more
wiley   +1 more source

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management

Advanced Materials, EarlyView.
A soft contact lens sensor enables continuous, noninvasive monitoring of nocturnal intraocular pressure (IOP) under closed‐eye sleep conditions. By integrating a highly compliant inductive–capacitive circuit onto a commercial lens, the device achieves record sensitivity and stable performance.
Yumin Dai, Tristan Michael Long, Oluwabunmi T. Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu, Seokkyoon Hong, Kyeonghee Lim, Jinheon Jeong, Dawn Meyer Schneider, Hyerim Ra, Bryan W. Boudouris, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Chi Hwan Lee   +19 more
wiley   +1 more source

ХМАРНІ ПЛАТФОРМИ ЯК КЛЮЧ ДО ЕФЕКТИВНОГО ЗБЕРІГАННЯ ТА АНАЛІЗУ IOT-ДАНИХ

Кібербезпека: освіта, наука, техніка
Стрімкий розвиток Інтернету речей (IoT) спричинив суттєве зростання обсягів даних, що генеруються пристроями, сенсорами та автоматизованими системами. Це створює потребу у високопродуктивних рішеннях для їх зберігання, обробки та аналітики в реальному ...
Іван Кукулевський, Євгеній Сокирка, Андрій Толбатов   +2 more
doaj   +1 more source

Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies

Journal of Translational Medicine, 2011
Background Glutamate excitotoxicity is thought to be involved in the pathogenesis of neurodegenerative disease. One potential source of glutamate is N-acetyl-aspartyl-glutamate (NAAG) which is hydrolyzed to glutamate and N-acetyl-aspartate (NAA) in a ...
Ebenezer Gigi J, Zhao Ming, Rudek Michelle A, Polydefkis Michael, Stathis Marigo, Rojas Camilo, Slusher Barbara S   +6 more
doaj   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

Advanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang, Tao Jiang, Zhongyue Lu, Dapeng Fan, Zucheng Yi, Zirong Luo   +5 more
wiley   +1 more source

Anticancer Activity of Polysaccharides Produced from Glycerol and Crude Glycerol by an Endophytic Fungus Chaetomium globosum CGMCC 6882 on Human Lung Cancer A549 Cells

Biomolecules, 2018
Two polysaccharides were produced by Chaetomium globosum CGMCC 6882 from glycerol (GCP-1) and crude glycerol (GCP-2). Chemical characteristics results showed GCP-1 and GCP-2 were similar polysaccharides, but the molecular weights of GCP-1 and GCP-2 were ...
Zichao Wang, Peizhang Chen, Ning Tao, Huiru Zhang, Ruifang Li, Xiaobei Zhan, Fuzhuan Wang, Yingben Shen   +7 more
doaj   +1 more source

Synergistic 3D Porous Architectures and Halogen Redox Chemistry for High‐Energy and High‐Power Microbatteries

Advanced Science, EarlyView.
3D porous Ni scaffolds with PANI cathode, Zn anode, and halogen redox chemistry synergistically enhance on‐chip microbattery performance by improving active material loading, Zn2+ diffusion, and charge‐transfer kinetics. The resulting 3D Zn//I2 microbatteries deliver high areal capacity, high energy and power density, and excellent cycling stability ...
Yijia Zhu, Monojit Mondal, Xiaopeng Liu, Nibagani Naresh, Firoz Alam, Mingqing Wang, Buddha Deka Boruah   +6 more
wiley   +1 more source

Sustainable Carbon Fibers Enable Stable Long‐Term Lithium Metal Deposition for Prospective Zero‐Excess Lithium Metal Batteries

Advanced Energy Materials, EarlyView.
This work presents lightweight, lignin‐derived carbon fiber current collectors that enable controlled lithium deposition. Structural defects and intermediate‐sized pores stabilize pre‐nucleation quasi‐metallic lithium clusters, promoting uniform lithium plating and stripping.
Samantha L. S. Southern, Jonathon Cottom, Jana B. Fritzke, Emma N. Antonio, Zhenyu Guo, Bhavini Patel, Romain Tort, Ifan E. L. Stephens, Camilla Di Mino, Clare P. Grey, Rhodri Jervis, Emilia Olsson, Heather Au, Maria‐Magdalena Titirici   +13 more
wiley   +1 more source