Results 71 to 80 of about 6,323 (304)

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

Clinical Pharmacology &Therapeutics, EarlyView.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell, Antonio Lombardi, William Brumskine, Lali Mikiashvili, Kim Boekelheide, Joanna Moreira, Alda Holsta, Matthew Betteridge, Lindsay Thompson, Angela Crook, Paul Bruinenberg, Maria Beumont, Eugene Sun, Francesca Conradie   +13 more
wiley   +1 more source

Deletion of Gli3 in mice causes abnormal frontal bone morphology and premature synostosis of the interfrontal suture

Frontiers in Physiology, 2012
Greig cephalopolysyndactyly syndrome (GCPS) is an autosomal dominant disorder with polydactyly and syndactyly of the limbs and a broad spectrum of craniofacial abnormalities.
Lotta eVeistinen, Maarit eTakatalo, Dörthe A. Kesper, Andrea eVortkamp, David P Rice, David P Rice   +5 more
doaj   +1 more source

Advances in Design Strategy and Mechanism Insights for Alkaline Hydrogen Evolution Reaction: Multilevel Site Engineering and Structure–Activity Relationship

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review is about material design based on engineering multilevel sites from theoretical calculation and synthetic routes to mechanism, structure–activity relationship, challenges and perspectives for boosting hydrogen production in alkaline electrolyte. Electrolytic water splitting is a clean, carbon‐free method for producing green hydrogen and has
Ke Zhang, Hongying Luo, Yudong Du, Kehao Yu, Huayu Wu, Shimin Chai, Yanyan Liu, Yongfeng Wang, Jianchun Jiang, Baojun Li   +9 more
wiley   +1 more source

Analysis of UAS Flight Altitude and Ground Control Point Parameters on DEM Accuracy along a Complex, Developed Coastline

Remote Sensing, 2020
Measuring beach topography accurately and with high spatial resolution is an important aspect of coastal management and is crucial for understanding changes in beach morphology, especially along complex, three-dimensional shorelines.
Taylor Zimmerman, Karine Jansen, Jon Miller   +2 more
doaj   +1 more source

mGFP-labeled, postmitotic migrating GCPs in the EGL with trailing and leading processes at P8.

, 2014
Left: P3-injected P8 cerebellum, mGFP  =  cells after recombination, mTomato  =  cells without recombination. Frames A-C are shown enlarged, A′-C′  =  further enlargement to show mGFP-immunoreactive GCPs in the inner EGL, A″-C″  =  mTomato. Arrowheads in
Thomas Günther (247952), Joachim Herz (28421), Petra May (581258), Roland Schüle (169570), Laura Steller (581257), Theresa Pohlkamp (581256), Michael Frotscher (226745), Hans H. Bock (447018)   +7 more
core   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

Forest Height Extraction Using GF-7 Very High-Resolution Stereoscopic Imagery and Google Earth Multi-Temporal Historical Imagery

Journal of Remote Sensing
With the advent of very high-resolution (VHR) imaging satellites, it is possible to measure the heights of forest stands or even individual trees more accurately.
Wenjian Ni, Zijia Li, Qiang Wang, Zhiyu Zhang, Qingwang Liu, Yong Pang, Yating He, Zengyuan Li, Guoqing Sun   +8 more
doaj   +1 more source

Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development

Scientific Reports, 2017
In the developing hippocampus, granule cell progenitors (GCPs) arising in the ventricular zone (VZ) migrate to the subpial region, and form the granule cell layer (GCL) of the dentate gyrus (DG).
Yuka Mimura-Yamamoto, Hiroshi Shinohara, Taichi Kashiwagi, Toru Sato, Seiji Shioda, Tatsunori Seki   +5 more
doaj   +1 more source

Gcps of two altered anchoring centers in mutants exhibit the same coordinated changes as in WT

, 2011
Copyright information:Taken from "Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers"http://www.neuraldevelopment.com/content/2/1/26Neural Development 2007;2():26-26.Published online 3 Dec 2007PMCID ...
Alexandra L Joyner (41120), Anamaria Sudarov (41119)   +1 more
core   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source