Results 51 to 60 of about 15,451 (255)

Towards testing a two-Higgs-doublet model with maximal CP symmetry at the LHC: construction of a Monte Carlo event generator [PDF]

open access: yes, 2012
A Monte Carlo event generator is constructed for a two-Higgs-doublet model with maximal CP symmetry, the MCPM. The model contains five physical Higgs bosons; the $\rho'$, behaving similarly to the standard-model Higgs boson, two extra neutral bosons $h'$
ATLAS Collaboration   +31 more
core   +2 more sources

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Nanogel, a versatile nanoscopic platform for the simultaneous delivery of acyclovir and lignocaine for the treatment of Herpes simplex virus infection: formulation and characterizations

open access: yesNano Express
This study was designed to develop a nanogel formulation incorporating acyclovir and lignocaine (ALN). Various formulations were developed in which ALN-V (formulation-V) was optimized.
Adnan Aslam   +3 more
doaj   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis   +5 more
wiley   +1 more source

Preparation and applications of guard cell protoplasts from the leaf epidermis of Solanum lycopersicum

open access: yesPlant Methods, 2018
Background Guard cell protoplasts (GCPs) isolated from various plants have proven to be especially useful for studies of signal transduction pathways and plant development.
Xuehui Yao   +5 more
doaj   +1 more source

Accuracy Assessment of a UAV Direct Georeferencing Method and Impact of the Configuration of Ground Control Points

open access: yesDrones, 2022
Unmanned aerial vehicles (UAVs) can obtain high-resolution topography data flexibly and efficiently at low cost. However, the georeferencing process involves the use of ground control points (GCPs), which limits time and cost effectiveness.
Xiaoyu Liu   +5 more
doaj   +1 more source

Co-Registration of Optically Sensed Images and Correlation (COSI-Corr): an Operational Methodology for Ground Deformation Measurements [PDF]

open access: yes, 2008
Recent methodological progress, Co-Registration of Optically Sensed Images and Correlation, outlined here, makes it possible to measure horizontal ground deformation from optical images on an operational basis, using the COSI-Corr software package ...
Avouac, Jean-Philippe   +3 more
core   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

Beyond Greenwashing: Impact of Circular Economy Practices on Green Collaborative Practices and Sustainable Supply Chain Integration Through Green Value Co‐Creation

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines the influence of circular economy practices, as a manifestation of corporate social responsibility, on green value co‐creation and its subsequent effects on green collaborative practices and sustainable supply chain integration between providers and customers.
Adriana Santos   +2 more
wiley   +1 more source

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