Results 51 to 60 of about 6,323 (304)

Nanogel, a versatile nanoscopic platform for the simultaneous delivery of acyclovir and lignocaine for the treatment of Herpes simplex virus infection: formulation and characterizations

open access: yesNano Express
This study was designed to develop a nanogel formulation incorporating acyclovir and lignocaine (ALN). Various formulations were developed in which ALN-V (formulation-V) was optimized.
Adnan Aslam   +3 more
doaj   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

Preparation and applications of guard cell protoplasts from the leaf epidermis of Solanum lycopersicum

open access: yesPlant Methods, 2018
Background Guard cell protoplasts (GCPs) isolated from various plants have proven to be especially useful for studies of signal transduction pathways and plant development.
Xuehui Yao   +5 more
doaj   +1 more source

Implementing GCPs in Asia [PDF]

open access: yesThe Quality Assurance Journal, 2000
The implementation of International Conference on Harmonization (ICH)-Good Clinical Practice (GCP) standards in China, Taiwan, Thailand and Japan poses some unique challenges due to cultural influences, particularly in Japan. Auditing experiences were generally positive in all countries with auditing by a Western company being viewed as a positive and ...
openaire   +1 more source

Gcps in the emerging fissures have a shorter mitotic index than other gcps

open access: yes, 2011
Copyright information:Taken from "Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers"http://www.neuraldevelopment.com/content/2/1/26Neural Development 2007;2():26-26.Published online 3 Dec 2007PMCID ...
Alexandra L Joyner (41120)   +1 more
core   +1 more source

Geometric Accuracy Analysis of Regional Block Adjustment Using GF-7 Stereo Images without GCPs

open access: yes, 2023
As an important means of improving positioning accuracy, block adjustment has been used in the improvement and assessment of accuracy for the Chinese Gaofen-7 (GF-7) satellite.
Xinming Tang   +3 more
core   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

Accuracy Assessment of a UAV Direct Georeferencing Method and Impact of the Configuration of Ground Control Points

open access: yesDrones, 2022
Unmanned aerial vehicles (UAVs) can obtain high-resolution topography data flexibly and efficiently at low cost. However, the georeferencing process involves the use of ground control points (GCPs), which limits time and cost effectiveness.
Xiaoyu Liu   +5 more
doaj   +1 more source

WNT3 activates the MAPK/ERK1,2 and ERK5 signaling pathway(s) in GCPs.

open access: yes, 2013
(A,B) GCPs were treated with WNT3 for 24 h and lysates analyzed by Western blot analysis. (A) WNT3 increases ERK1/2 and ERK5 phosphorylation in GCPs. Protein extracts were analyzed by immunoblotting with anti-P-ERK1/2, anti-ERK1/2, anti-P-ERK5, and anti ...
Eve-Ellen Govek (489756)   +8 more
core   +1 more source

Population pharmacokinetics and pharmacodynamics of canagliflozin in paediatric patients with type 2 diabetes mellitus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Canagliflozin was recently approved in type 2 diabetes mellitus (T2DM) patients ≥10 and <18 years old as a single agent dosed once daily (QD) or in a fixed‐dose combination with metformin dosed twice daily (BID). We characterize canagliflozin pharmacokinetics in paediatric patients with T2DM, compare estimated individual and simulated ...
Nele Goeyvaerts   +6 more
wiley   +1 more source

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