Results 161 to 170 of about 401,087 (313)

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Synthesis of 4'-C-α-Aminoethoxy-2'-O-Methyl-5-Methyl- and 5-Propynyl-Uridine Phosphoramidites for Structurally Optimized Antisense Oligonucleotides. [PDF]

Curr Protoc
Mahmoud EM, Ueno Y.
europepmc   +1 more source

Preparation of ^|^alpha;-Cyclodextrin-Modified Silica Gel and Its Application for Liquid Chromatography

, 1992
Munekazu Tsujimoto, Yoshio Saitō, Yoshio Matsubara, Seishiro IT Ocirc, Masakuni Yoshihara, Toshihisa Maeshima   +5 more
openalex   +2 more sources

Temperature dependent separation of metallic and semiconducting carbon nanotubes using gel agarose chromatography [PDF]

, 2015
Iskandar Yahya, Francesco Bonaccorso, S. K. Clowes, Andrea C. Ferrari, S. Ravi P. Silva   +4 more
openalex   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

The Discovery of Antibacterial Cembranoids from the Soft Coral <i>Lobophytum crassum</i> by DeepSAT Analysis. [PDF]

Mar Drugs
Wu B, Yao LG, Su MZ, Hou GG, Li SW, Guo YW.   +5 more
europepmc   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-<i>b</i>]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists. [PDF]

J Med Chem
Blua F, Boccato F, Buccellati C, Risè P, Barbieri S, Castiglioni L, Balzulat A, Rolando B, Marini E, Balestra M, Introvigne ML, Giorgis M, Sironi L, Tacconelli S, Hiesinger K, Patrignani P, Schmidtko A, Steinhilber D, Proschak E, Sala A, Rovati GE, Bertinaria M.   +21 more
europepmc   +1 more source

Gel chromatography of humic substances of lacustrine origin

, 1980
A. P. P. Toledo, Isabel Jordan, M.C Ferreroni   +2 more
openalex   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source