Results 181 to 190 of about 729,666 (303)

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Stereocontrolled Synthesis of Dimethylamino Phosphorochloridate Monomers toward Stereopure Phosphorodiamidate Morpholino Oligonucleotides. [PDF]

J Org Chem
Inutake R, Hasegawa H, Tsurusaki T, Sakamoto T, Sato K, Wada T.   +5 more
europepmc   +1 more source

Catalytic enantioselective alkene epoxidation using novel spirocyclic N-carbethoxy-azabicyclo[3.2.1]octanones

, 2010
Armstrong, A, Bettati, M, White, AJP
core   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Enhanced production of Nattokinase by Bacillus aryabhattai RP6 isolated from fermented Brassica oleracea. [PDF]

BMC Biotechnol
Prasanna R, Kundu D, Mohanan M, Vaithilingam M, Chandrasekaran SD.   +4 more
europepmc   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Purification of SlREC2 from wild-type tomato leaflets using immunoaffinity chromatography and immunoprecipitation. [PDF]

Front Plant Sci
Zhu L, Larkin RM.
europepmc   +1 more source

Gel Filtration Chromatography [PDF]

, 2020
openaire   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Synthesis of Avenanthramide C and Its Analogs Utilizing Classical Condensation, Saponification and Acidification. [PDF]

ACS Omega
Choi SM, An YJ, Nam YE, Kwon SJ, Choi ER, Cho JH.   +5 more
europepmc   +1 more source