Results 231 to 240 of about 401,087 (313)

Exploring the Uncharted Indolizine Chemical Space: Construction of 5‐Acylindolizines via a Domino Aldol–Vinylogous Aldol Process

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A domino aldol condensation–intramolecular vinylogous aldol condensation process was implemented for the first time to enable access to a wide range of novel 5‐acylated indolizines with a hydrogen, an alkyl, an aryl, or an alkoxy moiety at the C7 site.
Dohui Ku, Sunhee Lee, Ikyon Kim
wiley   +1 more source

Scalable purification enables high-quality virus-like particles for therapeutic translation. [PDF]

open access: yesJ Biol Chem
Hołubowicz R   +13 more
europepmc   +1 more source

Development of a Copper‐Free Click Reaction for Asymmetric Rh Diene Catalysis Under Confinement

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A copper‐free amino–yne click reaction enables the selective functionalization of chiral diene ligands with both soluble and immobilized amines. Substituent‐controlled stereoselectivity affords (E)‐ and (Z)‐enaminone ligands, which are converted into Rh complexes for asymmetric catalysis under homogeneous and heterogeneous conditions.
Manuel Kirchhof   +10 more
wiley   +1 more source

Harnessing Carbenoid Reactivity From Imidazoles and Oxiranes

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The combination of azole compounds and oxiranes exhibits carbenoid reactivity at elevated temperatures, as demonstrated by the successful benzoin condensation of aromatic aldehydes. Using this catalytic system to polymerize bifunctional aldehyde/oxirane monomers yields thermosets with glass transition temperatures above 100°C.
Matthias R. Steiner   +4 more
wiley   +1 more source

A plug and play approach to structural variations of bio-inspired anticancer lipidic phenyl dialkynylcarbinols. [PDF]

open access: yesRSC Adv
Bossuat M   +10 more
europepmc   +1 more source

Domino Synthesis of Functionalized Cyclic Acetals From Organic Carbonates

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Cyclic carbonates equipped with acrylic functional groups are shown to undergo a domino process in the presence of a suitable alkoxide to deliver novel types of decorated cyclic acetals. The developed protocol combines practical conditions and a wide scope and features a new reactivity modus for these carbon dioxide‐derived heterocyclic precursors.
Natalia Kulbacka   +5 more
wiley   +1 more source

Total Synthesis of Peniterphenyls A and E. [PDF]

open access: yesMar Drugs
Xu H   +6 more
europepmc   +1 more source

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