Results 261 to 270 of about 1,713,569 (328)

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

An Inexpensive System for Rapid and Accurate On-site Detection of Garlic-Infected Viruses by Agarose Gel Electrophoresis Followed by Array Assay. [PDF]

Plant Pathol J
Furuta K, Kawakubo S, Sasaki J, Masuta C.   +3 more
europepmc   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Serum protein electrophoresis in European mink (Mustela lutreola): reference intervals and comparison of agarose gel electrophoresis and capillary zone electrophoresis. [PDF]

Vet Q
Villanueva-Saz S, Aranda MDC, Jiménez MLÁ, de Andrés PJ, Verde M, Climent M, Lebrero Berna ME, Marteles Aragüés D, Fernández A.   +8 more
europepmc   +1 more source

Virulence genes and pulsed-field gel electrophoresis profiles of Shiga toxin-producing Escherichia coli isolated from different food samples and patients with acute diarrhea. [PDF]

Iran J Microbiol
Bonyadian M, Isvand Haidari F, Sami M.
europepmc   +1 more source

Agarose Gel Electrophoresis

Cold Spring Harbor Protocols, 2019
This protocol describes steps for the preparation and running of agarose gels and for staining and visualization of DNA in gels using three dyes: ethidium bromide, SYBR Gold, and SYBR Green 1.
Michael R, Green, Joseph, Sambrook
openaire   +3 more sources

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Agarose Gel Electrophoresis

Scandinavian Journal of Clinical and Laboratory Investigation, 1972
A simple technique for agarose gel electrophoresis allowing the simultaneous separation of 15 samples in less than one hour is described.
B. Johansson
openaire   +3 more sources

Gel Electrophoresis

Definitions, 2011
Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix.
Phil Vercoe, Agarose Gel Well
semanticscholar   +3 more sources

Polyacrylamide Gel Electrophoresis

Cold Spring Harbor Protocols, 2020
Cross-linked chains of polyacrylamide can be used as electrically neutral gels to separate double-stranded DNA fragments according to size and single-stranded DNAs according to size and conformation. Polyacrylamide gels have the following three major advantages over agarose gels: (1) Their resolving power is so great that they can separate molecules of
Michael R, Green, Joseph, Sambrook
openaire   +2 more sources