Results 261 to 270 of about 3,553,338 (335)

Investigation on appearance, texture, and molecular structure of heat-alkali synergistically induced egg white gel. [PDF]

Food Chem X
Yang S, Zhao Y, Wu N, Yao Y, Xu L, Chen S, Tu Y.   +6 more
europepmc   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement. [PDF]

Theranostics
Zhang F, Cheng J, Peng X, Zhang C, Qu L, Zhang S, Zhang J, Zhu S.   +7 more
europepmc   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

An affordable and simple method for DNA extraction from agarose suitable for downstream applications. [PDF]

Sci Rep
Sánchez-Flores JE, Sandoval-Cabrera A, Alarcón-Valdés P, Santillán-Benítez JG.   +3 more
europepmc   +1 more source

DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics

Advanced Science, EarlyView.
A molecular computing approach is presented with weighted signal amplification. Polymerase‐mediated strand displacement is employed to assign weights to target miRNAs, reflecting the miRNAs’ diagnostic values, followed by amplification of the weighted signals using localized DNA catalytic hairpin assembly.
Hongyang Zhao, Yumin Yan, Linghao Zhang, Xin Li, Lan Jia, Liang Ma, Xin Su   +6 more
wiley   +1 more source

A New Polymorphic Protein in Dog Serum Detected by SDS-Polyacrylamide Gel Electrophoresis

, 1982
Haruhiro Yoshida, Shigenori Ikemoto
openalex   +2 more sources

MALDI-TOF/TOF de novo sequence analysis of 2-D PAGE-separated proteins from Halorhodospira halophila, a bacterium with unsequenced genome [PDF]

, 2006
Debyser, Griet, Devreese, Bart, Memmi, Samy, Samyn, Bart, Sergeant, Kjell, Van Beeumen, Jozef   +5 more
core   +2 more sources

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

Clear Native Gel Electrophoresis for the Purification of Fluorescently Labeled Membrane Proteins in Native Nanodiscs

Ezsias B, Goessweiner-Mohr N, Siligan C, Horner A, Vargas C, Keller S, Pohl P.   +6 more
europepmc   +1 more source