Results 261 to 270 of about 856,230 (338)

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Comparative Electrophoretic Analysis Between the Protein Content in Human and Donkey Milk Samples-A Study Covering the Long-Term Lactation Period. [PDF]

Foods
Georgieva AS, Naydenova N, Ivanova D.
europepmc   +1 more source

Ribosomal Proteins, XII. Number of Proteins in Small and Large Ribosomal Subunits of Escherichia coli as Determined by Two-Dimensional Gel Electrophoresis

, 1970
E. Kaltschmidt, H. G. Wittmann
openalex   +2 more sources

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Proteome Analysis of the Six-Eyed Sand-Spider <i>Sicarius thomisoides</i> Venom. [PDF]

Toxins (Basel)
Arán-Sekul T, San Francisco J, Rojas J, Moon KM, Foster L, Catalán A.   +5 more
europepmc   +1 more source

Gel electrophoresis of proteins and enzymes

, 2023
Feret, P. P., Bergmann, F., Miksche, J. P.   +2 more
openaire   +1 more source

Analysis of differentially expressed proteins in Muscovy duck embryo fibroblasts infected with virulent and attenuated Muscovy duck reovirus by two-dimensional polyacrylamide gel electrophoresis

, 2017
Meiqing Huang, Xiaoxia Cheng, Shilong Chen, Min Zheng, Shaoying Chen   +4 more
openalex   +2 more sources

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

TetR- and LysR-type transcriptional regulators mediate multilayered control of T3SS1 by <i>Vibrio parahaemolyticus</i> quorum sensing. [PDF]

mBio
Zhang C, Wang Y, Wang C, Lu J, Yin H, Shi Y, Zhao Z.   +6 more
europepmc   +1 more source

Separation of the total proteins of <i>Novosphingobium pentaromativorans</i> US6-1 using SDS-polyacrylamide gel electrophoresis.

, 2015
Lyu Yihua, Wei Zheng, Zheng Tianling, Tian Yun   +3 more
openalex   +2 more sources