Results 71 to 80 of about 3,553,338 (335)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Electrophoresis of positioned nucleosomes [PDF]
, 2007 We present in this paper an original approach to compute the electrophoretic mobility of rigid nucleo-protein complexes like nucleosomes. This model allows to address theoretically the influence of complex position along DNA, as well as wrapped length of DNA on the electrophoretic mobility of the complex. The predictions of the model are in qualitative
arxiv +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
CHARACTERISATION OF IBD VIRAL PROTEINS IN SDS POLYACRYLAMIDE GEL ELECTROPHORESIS [PDF]
Journal of Veterinary and Animal Sciences, 2004 The field isolates of IBD virus was characterised using protein profile study. Four structural polypeptides of IBD virus with molecular weights of 91 K (VP1), 39 K (VP,), 32 K (VP3), and 28 K (VP4) and the additional polypeptide 47 K (VPX) preceusor ...
M. Parthiban, V. Thiagarajan
doaj
SDS Agarose Gels for Analysis of Proteins
BioTechniques, 1998 A new agarose-based protein electrophoresis gel system is described. The system consists of a highly resolving agarose, MetaPhor® XR (FMC BioProducts, Rockland, ME, USA) dissolved in urea and TBE buffer and a stacking gel composed of a high gel strength ...
Minjie Wu, Noriko Kusukawa
doaj +1 more source
The effect of high temperature on chemical structure of red blood corpuscles membranes for employees in ovens of Ramadi glass factory – Iraq. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 This study include investigation the effects of high temperature on the chemical structure of RBCs membranes in thirty workers of the state coperation of glass industries in Ramadi - Iraq , thirty technicians and administrators for interior control and ...
Safa Kamil Al-Amin +3 more
doaj +1 more source
Molecular Weight Distribution of Proteins Synthesized in Single, Identified Neurons of Aplysia [PDF]
, 1971 Parietovisceral ganglia from Aplysia californica were incubated in medium containing leucine-3H. Single, identified nerve cell somas were isolated from the ganglia, and their proteins extracted and separated by electrophoresis on 5% SDS-polyacrylamide ...
Wilson, David L.
core +4 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Studies on the major seed proteins of some grain crops [PDF]
, 1979 The general properties, classification and distribution of plant proteins are discussed within an agricultural context and the protein content and composition of several grain crops are tabulated.
Derbyshire, E.
core
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source