Results 101 to 110 of about 6,700,477 (288)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Enhancing the Gelation Behavior of Transglutaminase-Induced Soy Protein Isolate(SPI) through Ultrasound-Assisted Extraction

Foods
Gelation, as an important functional property of soy protein isolate (SPI), can be improved by some green technologies in food manufacturing, including ultrasound, ultrahigh pressure and microwave treatments.
Gaolin Li, Ran Tao, Yufeng Sun, Lili Wang, Yurui Li, Bei Fan, Fengzhong Wang   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Investigation of ultrasonic properties of MAGIC gels for pulse-echo gel dosimetry

, 2014
This thesis describes investigations into the design and evaluation of novel ultrasonic methods for 3-dimensional ionising radiation dose verification. Pulse-echo ultrasound methods were investigated for the measurement and analysis of complex radiation ...
Atkins, Timothy John
core   +1 more source

Effect of Konjac Glucomannan with Varying Molecular Weights on the Structure and Gel Properties of Frozen Antarctic Krill Myofibrillar Protein

Shipin gongye ke-ji
This study aimed to investigate the effects of konjac glucomannan (KGM) with varying molecular weights on the structure and gel properties of myofibrillar protein (MP) derived from frozen Antarctic krill.
Ming CHANG, Airong JIA, Miansong ZHANG, Xue LIU, Tingting CUI   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Effect of Composite Modification of Low Acyl Gellan Gum and Guar Gum on Gel properties of Brown Cattle Hide Gelatin

Shipin gongye ke-ji
Given the limitation of practical application caused by the poor gel properties of single gelatin, guar gum (GG), and low acyl gellan gum (LG) were used to modify the brown cattle hide gelatin.
Pengfei LI, Panzhifei WANG, Rozi PARHAT, Xiaojing YE, Mamat RIZWANGUL, Niyazmamat BUAJIER, Hongjiao HAN, Abulikemu BATUER   +7 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Creation of TGMS Lines of Waxy Rice with Elite Physicochemical Properties of Starch via Waxy Gene Editing

Foods
Waxy rice starch (WRS), characterized by low amylose content, high viscosity, and strong gel-forming ability, is highly valued in food and industrial applications.
Jun Zhu, Zhenchao Wang, Ruipeng Zhao, Weiyi Li, Tanghuang Gan, Jiaxin Wan, Haoliang Sun, Ying Liu, Min Wei, Hongyan Xu, Tingting Luo, Yonghuan Hua, Shuangcheng Li, Yuhao Fu, Ping Li   +14 more
doaj   +1 more source