Results 111 to 120 of about 6,700,477 (288)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Textural Properties of Carbopol® Gel with Curcumin and Curcumin–HPβCD Inclusion Complex and Biological Activities

The aim of this study was to prepare curcumin/2-hydroxypropyl-β-cyclodextrin (HPβCD) inclusion complex, evaluate the antioxidant and antimicrobial activities of curcumin and curcumin in inclusion complex, as well as to examine the effect of ...
Uro\u161evi\u107, Maja, Vesna Nikolić, Nikoli\u107, Vesna, Martinovi\u107, Milica, Ljubiša Nikolić, Savi\u107, Vesna, Maja Urošević, Dini\u107, Ana, Ana Dinić, Tatjana Mihajilov-Krstev, Gaji\u107, Ivana, Mihajilov-Krstev, Tatjana, Nikoli\u107, Ljubi\u161a, Ivana Gajić, Milica Martinović, Vesna Savić   +15 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Effects of Camellia oleifera Seed-Cake Crude Protein on the Gel Properties of Silver Carp Surimi

Shipin gongye ke-ji
To clarify the effect of Camellia oleifera seed-cake crude protein (COCP) on the gel properties of silver carp surimi, this study incorporated COCP at different concentrations and measured the gel’s water holding capacity, cooking loss, whiteness ...
Yufeng ZHENG, Dandan YU, Yiling LIU, Chenxi ZHANG, Zhaoyuan CHEN, Yidong XIAO, Ting HU   +6 more
doaj   +1 more source

Gelling properties of myofibrillar protein–soy protein and k-carrageenan composite as affected by various salt levels

International Journal of Food Properties, 2019
In order to increase use of soybean protein in meat products, the objective of this research was to investigate the effects of k-carrageenan on the gel properties of the myofibrillar protein (MP)–soybean protein isolate (SPI) composite with various salt ...
Jie Sun, Guoyou Yin, Jie Chen, Pengpeng Li   +3 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Gel properties of silver carp (Hypophthalmichthys molitrix) and chicken mixture gels as affected by setting temperatures

International Journal of Food Properties, 2018
This study aimed to evaluate the effect of setting temperatures (30°C, 35°C, 40°C, 45°C, and 50°C) on gel properties and protein profiles of paste gels derived from silver carp (Hypophthalmichthys molitrix) and chicken meat.
Ping Gui, Longteng Zhang, Hui Hong, Ligeng Feng, Yongkang Luo   +4 more
doaj   +1 more source

Improving the Quality of Low-Salt Beef Myofibrillar Protein Gels with L-Lysine and Konjac Glucomannan: Water Retention, Texture, and Protein Structural Changes

Gels
Reducing sodium in meat products is nutritionally desirable, but salt reduction often weakens myofibrillar protein gelation and reduces texture quality and water retention. This study investigated the effects of L-lysine (Lys) and konjac glucomannan (KGM)
Xiuyun Guo, Jinsheng Yang, Chao Fu, Jiangpeng Yao, Zhikun Yang, Xiangren Meng   +5 more
doaj   +1 more source