Results 151 to 160 of about 246,313 (305)

Gelatin-Based Hybrid Hydrogels as Matrices for Organoid Culture

The application of liver organoids is very promising in the field of liver tissue engineering; however, it is still facing some limitations. One of the current major limitations is the matrix in which they are cultured.
Louis Van der Meeren (8789918), Peter Dubruel (295194), Sandra Van Vlierberghe (7431617), André G. Skirtach (13184854), Luc J. W. van der Laan (10115113), Bart Spee (66184), Shicheng Ye (12588025), Maarten D. Delemarre (17734806), Kerstin Schneeberger (8785088), Nathan Carpentier (13184851)   +9 more
core   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

Advanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang, Gong Cheng, Wenyong Fei, Qiuzhen Liang, Liang Zhang, Kegui Liu, Jihang Dai, Bo Cong, Xu Hu, Zhonglian Wu, Jialu Zhang, Jinlan Cui, Hang Yao, Dong‐An Wang, Jingcheng Wang, Tao Sun, Jiang Zheng   +16 more
wiley   +1 more source

The Dissolution of Gelatin [PDF]

Biochemical Journal, 1924
openaire   +2 more sources

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Optimization of Hydrophobic Group Structures Covalently Incorporated into Gelatin Hydrogels for Efficient Adsorption and Release of Hydrophobic Drugs. [PDF]

Gels
Nishimura K, Matsumoto T, Kanamaru K, Kobaru S, Ishikawa T, Tatsumi Y, Shimoyama Y, Yoshida M, Takei T.   +8 more
europepmc   +1 more source

The Attachment of Tumor Cells to the Micropatterns of Glutaraldehyde (Ga)-Crosslinked Gelatin

, 2014
This work proposes a novel technique to induce the attachment of tumor cells to the micropatterns of glutaraldehyde (GA)-crosslinked gelatin. It provides another method to crosslink gelatin other than using the photo-sensitizing agents or selective GA ...
Ou, Yu-Cheng; Hsu, Chih-Wen; Yang, Lung-Jieh; Han, Hsieh-Cheng; Liu, Yi-Wen; Chen, Chien-Yuan
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Contrasting Effects of Chitosan Molecular Modifications on the Properties of Fish Gelatin Hydrogels. [PDF]

Int J Mol Sci
Nikiforova AA, Abramov V, Skvortsova PV, Akhmadiyarov AA, Rakipov IT, Sorokin AV, Lavlinskaya MS, Zueva OS, Holyavka MG, Derkach SR, Zuev YF.   +10 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Evaluation of Bone Regeneration by Sustained Release of Bone Morphogenetic Protein from Porous Polyetheretherketone. [PDF]

Int J Mol Sci
Shiotani Y, Jo JI, Takasugi S, Adachi T, Yasui K, Hashimoto Y, Nishiura A.   +6 more
europepmc   +1 more source