Results 201 to 210 of about 3,125,328 (279)

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

American Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

APOBEC3C coordinates DDX5 in R-loop resolution and dynamic control of Chk1-mediated stress-responsive circuitry as a prerequisite for gemcitabine resistance in p53-deficient cells. [PDF]

Cell Death Dis
Tao L, Zhao Y, Jiang Z, Kong S, Ding Y, Ni T, Wang W, Liu Y.   +7 more
europepmc   +1 more source

Supplementary figure S3 from Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation

, 2023
Huai‐Qiang Ju, Takeshi Gocho, Mitzi Aguilar, Min Wu, Zhuonan Zhuang, Jie Fu, Katsuhiko Yanaga, Peng Huang, Paul J. Chiao   +8 more
openalex   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy. [PDF]

Oncol Rep
Zheng R, Liu Y, Zhou S, Liu G, Liu X, Yang Y, Zhang Y.   +6 more
europepmc   +1 more source

ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1

, 2019
Yang Zhou, Yunjiang Zhou, Keke Wang, Tao Li, Minda Zhang, Yunjia Yang, Rui Wang, Rong Hu   +7 more
openalex   +1 more source

A Novel MPT‐Driven Necrosis‐Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Mitochondrial permeability transition (MPT)‐driven necrosis, a recently identified form of programmed cell death, significantly influences tumor progression, therapy response, and prognosis. However, research on mitochondrial permeability transition‐driven necrosis‐related long non‐coding ribonucleic acids (MPTDNRlncRNAs) in ...
Yang Liu, Liye Tao, Zefeng Shen, Junhao Zheng, Yali Wang, Meijie Chen, Yangyang Xie, Hongjun Chen, Jingwei Cai, Haoyu Pan, Shihao Li, Renan Jin, Junjie Xu, Xiao Liang   +13 more
wiley   +1 more source

Delayed Diagnosis of Sézary Syndrome: Lessons From a Psoriasiform Presentation

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Pruritic erythroderma is not always psoriasis. Resistant cases require a broad evaluation for cutaneous lymphoma. Early, timely diagnosis prevents disease progression, improves outcomes, and enhances quality of life, highlighting the need for re‐evaluation when conventional treatments fail.
Sudhan Neupane, Anu Neupane, Sajjad Ahmed Khan, Huma Kausar   +3 more
wiley   +1 more source

Gemcitabine resistance by CITED4 upregulation via the regulation of BIRC2 expression in pancreatic cancer. [PDF]

J Biomed Sci
Jeong EJ, Roh Y, Jung E, Hwang JS, Son T, Ban HS, Han TS, Choo YK, Kim JS.   +8 more
europepmc   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source