Suicide gene therapy on spontaneous canine melanoma: correlations between in vivo tumors and their derived multicell spheroids in vitro [PDF]
To validate the use of multicellular spheroids to predict the efficacy of herpes simplex thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene therapy in the respective in vivo tumors, we established and characterized 15 melanoma-derived cell lines from ...
Altamirano, Natalia Andrea+6 more
core +1 more source
Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]
Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia+5 more
core +3 more sources
Brucella and Osteoarticular Cell Activation: Partners in Crime [PDF]
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis.
Adamopoulos+95 more
core +1 more source
The significance of cytogenetics for the study of karyotype evolution and taxonomy of water bugs (Heteroptera, Belostomatidae) native to Argentina [PDF]
Male meiosis behaviour and heterochromatin characterization of three big water bug species were studied. Belostoma dentatum (Mayr, 1863), B. elongatum Montandon, 1908 and B. gestroi Montandon, 1903 possess 2n = 26 + X1X2Y (male).
Bressa, Maria Jose+2 more
core +2 more sources
EFEITO DA SEXAGEM E LINHAGENS SOBRE O DESEMPENHO E RENDIMENTO DE CARCAÇA DE FRANGOS DE CORTE
Realizou-se este trabalho com o objetivo de avaliar o desempenho produtivo e o rendimento de carcaça de diferentes linhagens e sexagens de frangos de corte.
Ivandro Api+5 more
doaj +1 more source
Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen+5 more
core +1 more source
High levels of human infection with Trypanosoma cruzi associated with the domestic density of infected vectors and hosts in a rural area of northeastern Argentina [PDF]
Background: Insecticide spraying campaigns designed to suppress the principal vectors of the Chagas disease usually lack an active surveillance system that copes with house reinvasion.
Cardinal, Marta Victoria+5 more
core +1 more source
Effects of the Invasive Freshwater Mussel Limnoperna fortunei on Sediment Properties and Accumulation Rates [PDF]
Since its introduction into South America around 1990, the freshwater bivalve Limnoperna fortunei (the golden mussel) has spread rapidly and is now a dominant component of the benthic and periphytic fauna in many rivers, lakes, and reservoirs.
Barbosa+79 more
core +1 more source
Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells [PDF]
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related death worldwide. Current treatments are extremely disappointing.
Alaniz, Laura Daniela+8 more
core +1 more source
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common genetic cause of ischemic strokes and a most important model for the study of subcortical vascular dementia.
Charles André
doaj +1 more source