Results 71 to 80 of about 766,696 (285)

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Gender-based violence and reproductive health in five Indian states [PDF]

, 2012
Gender-based violence is a multi-faceted public health problem with numerous consequences for an individual’s physical and mental health and wellbeing. This collection develops a comprehensive public health approach for working with gender-based violence,
Coast, Ernestina, Leone, Tiziana, Malviya, Alankar   +2 more
core  

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

SIKAP MASYARAKAT KUDUS TERHADAP UNDANG-UNDANG TENTANG PENGHAPUSAN KEKERASAN DALAM RUMAH TANGGA

Muwazah, 2012
This study is about PKDRT law. It gives us information that domestic violence is a real thing that happens in our society, especially in Kudus. On the one hand, civil society actually has a formula to prevent the authority and rights of their family life
Anisa Listiana dan M. Widjanarko
doaj   +1 more source

A Global Crime Against Women: Sex Trafficking and Its Consequences [PDF]

, 2018
Sex trafficking, a form of gender-based violence in which a specific gender is the target of violence due to the imbalance of power, is a common present-day global crime (Murturi 2006:83). Women are most often victims of this specific crime, (Muturi 2006:
Ferreira, Breezy
core   +1 more source

Sexual violence in Iraq: Challenges for transnational feminist politics [PDF]

, 2016
The article discusses sexual violence by ISIS against women in Iraq, particularly Yezidi women, against the historical background of broader sexual and gender-based violence.
Al-Ali N, Al-Ali N, Begikhani N, Cockburn C, Cockburn C, Cockburn C, Efrati N, Enloe C, Enloe C, Enloe C, Hardi C, Kanie M, Mojab S, Mojab S, Nadje Al-Ali, Omar S, Rohde A, Russell B, Wibben A, Wibben A   +19 more
core   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

An Exploration of Animal Metaphors in Gender-Based Violence Campaigns

Cultura, Lenguaje y Representación
This article explores the use of animal metaphors in gender-based violence campaigns. It analyzes a purpose-built corpus consisting of 39 public-awareness campaigns that run between 1998 to 2023 across 21 countries that resort to animal metaphors in the
Irene López-Rodríguez
doaj   +1 more source

Predictors and facilitators of gender-based violence in sub-Saharan Africa: a rapid review

Journal of Global Health Reports, 2019
# Background An understanding of factors associated with gender-based violence is essential for developing evidence-based interventions that are necessary for the prevention of violence against women.
Ifeyinwa C Akamike, Chigozie J Uneke, Henry C Uro-Chukwu, Ijeoma N Okedo-Alex, Onyedikachi E Chukwu   +4 more
doaj   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source