Results 211 to 220 of about 1,154,991 (281)

Additional file 2 of Genome-wide associated variants of subclinical atherosclerosis among young people with HIV and gene-environment interactions

, 2023
Jiayu He, Haijiang Lin, Yingying Ding, Xing Liu, Kelin Xu, Xiaoxiao Chen, Weiwei Shen, Sujuan Zhou, Miaochen Wang, Jingjing Xia, Na He   +10 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Ethical, Legal, and Social Implications of Gene-Environment Interaction Research. [PDF]

Genet Epidemiol
Calluori S, Heimke KK, Caga-Anan C, Kaufman D, Mechanic LE, McAllister KA.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Genome-wide association study identified novel loci and gene-environment interaction for refractive error in children. [PDF]

NPJ Genom Med
Wang Y, Zhang Y, Chen H, Zhang XJ, Zhang R, Ng TK, Tham JA, Kam KW, Tam POS, Young AL, Wei Y, Zhang M, Pang CP, Tham CC, Yam JC, Chen LJ.   +15 more
europepmc   +1 more source

Gene-environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. [PDF]

Personal Neurosci, 2023
Klingenberg B, Guloksuz S, Pries LK, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin BD, Luykx J, van Os J, Rutten BPF.   +17 more
europepmc   +1 more source

Gene and Environment Interactions in the Brain: A Pathway to ADHD? [PDF]

, 2015
Philip Shaw
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Gene-environment interaction modifies the association between hyperinsulinemia and serum urate levels through SLC22A12. [PDF]

J Clin Invest
Fujii W, Yamazaki O, Hirohama D, Kaseda K, Kuribayashi-Okuma E, Tsuji M, Hosoyamada M, Kochi Y, Shibata S.   +8 more
europepmc   +1 more source

The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders. [PDF]

Front Psychiatry, 2023
Shen G, Yang S, Wu L, Chen Y, Hu Y, Zhou F, Wang W, Liu P, Wu F, Liu Y, Wang F, Chen L.   +11 more
europepmc   +1 more source