β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Gene-Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy. [PDF]
Jasmine F +8 more
europepmc +1 more source
Elastic–Plastic Modeling and Experimental Characterization of Granular Jamming Actuators
Granular jamming enables rapid switching between soft and rigid mechanical states. Here, a reduced‐order elastic‐perfectly‐plastic beam framework captures pressure‐dependent loading, unloading, residual deformation, and hysteresis in jammed beams, while matching three‐point bending experiments across materials and geometries. The framework links design
Saheli Patel +2 more
wiley +1 more source
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti +16 more
wiley +1 more source
Refining the scope of genetic influences on alcohol misuse through environmental stratification and gene-environment interaction. [PDF]
Savage JE +6 more
europepmc +1 more source
Genome-Wide Gene-Environment Interaction Analysis Identifies Novel Candidate Variants for Growth Traits in Beef Cattle. [PDF]
Deng T +12 more
europepmc +1 more source
Investigating gene-environment interaction on attention in a double-hit model for Autism Spectrum Disorder. [PDF]
Maroon M +4 more
europepmc +1 more source
Gene-environment interaction between gaming addiction and perceived stress in late adolescents and young adults: A twin study. [PDF]
Hur YM.
europepmc +1 more source
Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia.
Rayinda T +8 more
europepmc +1 more source

