Results 91 to 100 of about 922,149 (303)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2014 Objective: To model the potential interaction between previously identified biomarkers in children sarcomas using artificial neural network inference (ANNI).
David J Boocock +14 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
BMC Primary CareBackground The management in primary care (PC) of the patients with Heart Failure (HF) is different from the management hospital, in a special way compared to cardiology departments.
Sergio Cinza-Sanjurjo +9 more
doaj +1 more source
Gene - environment interaction in programming hippocampal plasticity: focus on adult neurogenesis
Frontiers in Molecular Neuroscience, 2015 Interactions between genes and environment are a critical feature of development and both contribute to shape individuality. They are at the chore of vulnerability / resiliency for mental illnesses.
Muriel eKoehl, Muriel eKoehl
doaj +1 more source
, 2007 : The intelligent systems that design in an environment require models of environment. Autonomous learning agents, that start with no models of environment, need to generate models of environment.
Learn Model +2 more
core
Summary of gene-environment interaction results.
, 2013 Summary of gene-environment interaction results.
Yungling Leo Lee (176573) +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Genome-Wide Gene-Environment Interaction Analysis Using Set-Based Association Tests
Frontiers in Genetics, 2019 The identification of gene-environment interactions (G × E) may eventually guide health-related choices and medical interventions for complex diseases. More powerful methods must be developed to identify G × E.
Wan-Yu Lin +7 more
doaj +1 more source
Gene-environment interaction in the association of residential greenness and 25(OH) vitamin D
, 2023 There is increasing awareness for beneficial health effects of green space surrounding the home, but the underlying mechanisms are not yet fully understood and challenging to study given the correlation with other exposures.
Hicran Altug (20270820) +13 more
core