Results 101 to 110 of about 15,130,803 (334)

Oxytocin receptor gene (OXTR) and deviant peer affiliation: A gene-environment interaction in adolescent antisocial behavior [PDF]

, 2019
Although the oxytocin receptor gene (OXTR) is involved in aggression and social affiliation, it has not been examined in gene-environment interaction studies.
Iro Fragkaki, van Lier, Pol A.C., Branje, Susan J.T., Susan J. T. Branje, Koot, Hans M., Boks, Marco P., Leerstoel Branje, Dominique F. Maciejewski, Hans M. Koot, Verhagen, Maaike, Maaike Cima, Pol A. C. van Lier, Cima, Maaike, Meeus, Wim H.J., Maaike Verhagen, Branje, Susan J. T., Meeus, Wim H. J., Wim H. J. Meeus, Maciejewski, Dominique F., Van Lier, Pol A. C., Marco P. Boks, Fragkaki, Iro, Adolescent development: Characteristics and determinants, Brain, Maciejewski, D.F., Lier, P.A.C. van, Branje, S.J.T., Verhagen, M., Cima, M.J., Boks, M.P.M., Koot, J.M., Meeus, W.H.J., UMC Utrecht, Fragkaki, I., Onderzoeksgroep 2   +34 more
core   +3 more sources

Random regression models for detection of gene by environment interaction

Genetics Selection Evolution, 2007
Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts ...
Meuwissen Theo HE, Ødegård Jørgen, Lillehammer Marie   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

GIS mapping and gene-environment interaction

, 2014
Gene-environment interaction and GIS mapping were two major methods for spatial data analysis in public health sector. In the past, researchers often used the gene-environment interaction method to study the relationship between the environmental ...
Zhu, Jialing
core   +1 more source

The Impact of Gene–Environment Interaction on Alcohol Use Disorders

Alcohol Research, 2012
This article describes three types of gene–environment interactions and the challenges inherent in interpreting these interactions. It also reports on what is known about gene–environment interactions in the field of alcohol use disorders ...
Danielle M. Dick, Kenneth S. Kendler
doaj   +1 more source

MAOA, childhood maltreatment and antisocial behavior: Meta-analysis of a gene-environment interaction

Biological Psychiatry, 2013
Background In a seminal study of gene-environment interaction, childhood maltreatment predicted antisocial behavior more strongly in males carrying an MAOA promoter variant of lesser, compared to higher, transcriptional efficiency.
A. Byrd, S. Manuck
semanticscholar   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Why Many Geneticists and Psychological Scientists Have Discrepant Views About Gene–Environment Interaction (G×E) Research

American Psychologist, 2014
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders, many traditional psychological and social science researchers have added, or plan to add, genetic components to their programs of research. An understanding of the
L. Duncan, Alisha R. Pollastri, J. Smoller   +2 more
semanticscholar   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source